Purpose Pain in the neonate is often challenging to assess but important to control.
Physicians often must balance the need for optimal pain control with the need to minimize …

Multiple lines of evidence suggest an increased sensitivity to pain in neonates. Repeated
and prolonged pain exposure may affect the subsequent development of pain systems, as …

Neonatal care is advancing to levels where more neonates are now offered more invasive
interventions, exposing them to more prolonged hospital care. Consequently, the provision …

Inadequate pain management but also inappropriate use of analgesics in early infancy has
negative effects on neurodevelopmental outcome. As a consequence, neonatal pain …

Management of painful procedures in the neonate is less than optimal. Although evidence
exists to support the infant's capacity to feel pain at birth, health professionals do not …

Premature infants hospitalized after birth are exposed to repeated painful procedures as part
of their routine medical care. Early neonatal exposure to unmanaged pain has been linked …

Health care professionals caring for neonates (birth to 28 days of life) and infants up to 1
year of age have a professional and ethical responsibility to provide safe and effective pain …

Opioids for procedural pain in neonates - Kinoshita, M - 2023 | Cochrane Library Skip to
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Background Neonates are an extremely vulnerable patient population, with 6% to 9%
admitted to the neonatal intensive care unit (NICU) following birth. Neonates admitted to the …

Background Continuous opioid infusion (COI) remains the mainstay of analgesic therapy in
the neonatal intensive care unit (NICU). Parent/nurse‐controlled analgesia (PNCA) has …