Reliability of monitoring the clinical dementia rating in multicenter clinical trials

KA Schafer, RE Tractenberg, M Sano… - Alzheimer Disease & …, 2004 - journals.lww.com
Objective: To demonstrate the degree of agreement on CDR scoring of clinical monitors
working independently from ADCS-CDR worksheets. Design: Three members of the ADCS …

Interobserver disagreements on clinical dementia rating assessment: interpretation and implications for training

RE Tractenberg, K Schafer… - Alzheimer Disease & …, 2001 - journals.lww.com
Abstract The Clinical Dementia Rating (CDR) is a widely used semiobjective instrument for
staging dementia severity. A global CDR score is reported that is derived from individual …

The SIST-M: predictive validity of a brief structured clinical dementia rating interview

OI Okereke, N Pantoja-Galicia… - Alzheimer Disease & …, 2012 - journals.lww.com
Background: We have previously established the reliability and cross-sectional validity of the
SIST-M (Structured Interview and Scoring Tool–Massachusetts Alzheimer's Disease …

Sample size requirements for training to a κ agreement criterion on clinical dementia ratings

RE Tractenberg, F Yumoto, S Jin… - Alzheimer Disease & …, 2010 - journals.lww.com
Abstract The Clinical Dementia Rating (CDR) is a valid and reliable global measure of
dementia severity. Diagnosis and transition across stages hinge on its consistent …

Rationale for use of the Clinical Dementia Rating Sum of Boxes as a primary outcome measure for Alzheimer's disease clinical trials

JM Cedarbaum, M Jaros, C Hernandez, N Coley… - Alzheimer's & …, 2013 - Elsevier
BACKGROUND: We used the database of the Alzheimer's Disease Neuroimaging Initiative
(ADNI) to explore the psychometric properties of the Clinical Dementia Rating Sum of Boxes …

[HTML][HTML] Psychometric properties of the Clinical Dementia Rating—Sum of Boxes and other cognitive and functional outcomes in a prodromal Alzheimer's disease …

F McDougall, C Edgar, M Mertes, P Delmar… - The Journal of …, 2021 - Springer
Abstract Background The Clinical Dementia Rating-Sum of Boxes (CDR-SB) has been
proposed as a primary outcome for use in prodromal AD trials. However, the psychometric …

The “portable” CDR: translating the clinical dementia rating interview into a PDA format

JE Galvin, TM Meuser, MA Coats… - Alzheimer Disease & …, 2009 - journals.lww.com
Abstract The Clinical Dementia Rating (CDR) is a common rating system used in clinical
trials and longitudinal research projects to rate the presence and severity of cognitive …

Suitability of the Clinical Dementia Rating-Sum of Boxes as a single primary endpoint for Alzheimer's disease trials

N Coley, S Andrieu, M Jaros, M Weiner… - Alzheimer's & …, 2011 - Elsevier
BACKGROUND: Clinical measures continue to be used as primary endpoints for disease-
modifying trials for Alzheimer's disease (AD). Currently, two co-primary endpoints must be …

Application of the Brazilian version of the CDR scale in samples of dementia patients

ALG Maia, C Godinho, ED Ferreira… - Arq. Neuro …, 2006 - arquivosdeneuropsiquiatria.org
OBJECTIVE: The objective of the study was the analysis of agreement between the CDR
scale with diagnostic criteria and mini mental state examination (MMSE), as well as …

Validation of the new interpretive guidelines for the clinical dementia rating scale sum of boxes score in the national Alzheimer's coordinating center database

SE O'Bryant, LH Lacritz, J Hall, SC Waring… - Archives of …, 2010 - jamanetwork.com
Background It was recently demonstrated that the Clinical Dementia Rating scale Sum of
Boxes (CDR-SB) score can be used to accurately stage severity of Alzheimer dementia and …