Objective Depression disorder is accompanied by cognitive impairments. However, there is
limited research focused on cognitive impairments and their neurological mechanism in …

Recent studies have indicated the potential clinical use of near infrared spectroscopy (NIRS)
as a tool in assisting the diagnosis of major depressive disorder (MDD); however, it is still …

Frontal lobe dysfunction has been implicated as one of the pathophysiological bases of
bipolar disorder. Detailed time courses of brain activation in the bipolar disorder group were …

Background Previous studies have shown the clinical effect of 2 Hz repetitive transcranial
magnetic stimulation (rTMS) for depression; however, its underlying neural mechanisms are …

The present study investigated functional changes of brain oxygenation in prefrontal brain
areas of nine depressed patients and nine age-and sex-matched healthy comparison …

Reduced oxygenation changes in the prefrontal cortex during cognitive tasks have been
reported in major depressive disorder (MDD). However, prefrontal asymmetry during …

Altered prefrontal brain activity (eg hypofrontality) during cognitive tasks such as working
memory is a core neuroimaging marker in unipolar (UNI) and bipolar (BI) depression. The …

BackgroundDeficits in frontal lobe perfusion have been demonstrated in late-life depression;
however, studies to date have generally involved small numbers, used neuroimaging rather …

Social anxiety disorder (SAD) is characterized by strong fear and anxiety during social
interactions. Although ventrolateral prefrontal cortex (VLPFC) activity in response to …

Major depressive disorder (MDD) and bipolar disorder (BD) patients show speech
characteristics that vary greatly according to mood state. In a previous study, we found …