[HTML][HTML] Detection of Chlamydia trachomatis ocular infection in trachoma-endemic communities by rRNA amplification

JL Yang, KC Hong, J Schachter… - … & visual science, 2009 - arvojournals.org
purpose. Trachoma remains the leading infectious cause of blindness worldwide. The World
Health Organization (WHO) recommends mass antibiotic distributions in its strategy to …

Comparison of an rRNA-based and DNA-based nucleic acid amplification test for the detection of Chlamydia trachomatis in trachoma

JL Yang, J Schachter, J Moncada, D Habte… - British journal of …, 2007 - bjo.bmj.com
Background/Aim: The World Health Organisation (WHO) hopes to achieve global elimination
of trachoma, still the leading cause of preventable blindness worldwide, in part through …

[HTML][HTML] Which members of a community need antibiotics to control trachoma? Conjunctival Chlamydia trachomatis infection load in Gambian villages

MJ Burton, MJ Holland, N Faal, EAN Aryee… - … & visual science, 2003 - arvojournals.org
purpose. Trachoma is the leading cause of infectious blindness worldwide. Control
strategies target antibiotic therapy to individuals likely to be infected with Chlamydia …

Evaluation of a Chlamydia trachomatis-specific, commercial, real-time PCR for use with ocular swabs

H Pickering, MJ Holland, AR Last, MJ Burton… - Parasites & vectors, 2018 - Springer
Background Trachoma, the leading infectious cause of blindness worldwide, is caused by
conjunctival Chlamydia trachomatis infection. Trachoma is diagnosed clinically by …

Reliability of clinical diagnosis in identifying infectious trachoma in a low-prevalence area of Nepal.

K Baral, S Osaki, B Shreshta, CR Panta… - Bulletin of the World …, 1999 - ncbi.nlm.nih.gov
Abstract The WHO Alliance for Global Elimination of Trachoma by 2020 has increased the
need to identify ocular chlamydial infections by clinical examination in areas of both high …

[HTML][HTML] Quality assessment of conjunctival specimens for detection of Chlamydia trachomatis by PCR in children with active trachoma

B De Barbeyrac, P Goldschmidt, S Malembic… - Clinical microbiology …, 2007 - Elsevier
One component of control programmes to eliminate trachoma is the treatment of Chlamydia
trachomatis infection. A diagnosis of trachoma is based on clinical grounds, but the signs of …

Does clinical diagnosis indicate ocular chlamydial infection in areas with a low prevalence of trachoma?

J Thein, P Zhao, H Liu, J Xu, HC Jha… - Ophthalmic …, 2002 - Taylor & Francis
The WHO has initiated a global program to eliminate trachoma. This program includes mass
antibiotic administrations to reduce the prevalence of Chlamydia trachomatis, the causative …

Use of a Chlamydia trachomatis DNA probe for detection of ocular chlamydiae

D Dean, L Palmer, CR Pant, P Courtright… - Journal of clinical …, 1989 - Am Soc Microbiol
We examined the efficacy of a Chlamydia trachomatis DNA probe in detecting ocular
chlamydiae by comparing it with tissue culture isolation, direct fluorescent-antibody cytology …

Diagnostic Accuracy of a Prototype Point-of-Care Test for Ocular Chlamydia trachomatis under Field Conditions in The Gambia and Senegal

EM Harding-Esch, MJ Holland… - PLoS neglected …, 2011 - journals.plos.org
Background The clinical signs of active trachoma are often present in the absence of ocular
Chlamydia trachomatis infection in low prevalence and mass treated settings. Treatment …

Polymerase chain reaction for the detection of ocular chlamydial infection in trachoma-endemic communities

RL Bailey, TJ Hampton, LJ Hayes… - Journal of Infectious …, 1994 - academic.oup.com
Polymerase chain reaction (PCR) with primers derived from the sequence of the cryptic
chlamydial plasmid was evaluated for the detection of ocular chlamydial infection in …