Background Aneurysmal subarachnoid hemorrhage (aSAH) is often complicated by the
occurrence of delayed ischemic neurologic deficits (DIND), which impairs the clinical …

Secondary brain injury after aneurysmal subarachnoid hemorrhage (SAH-SBI) contributes to
poor outcomes in patients after rupture of an intracranial aneurysm. The lack of diagnostic …

Objective The aim of this study is to explore whether preoperative hemoglobin levels could
serve as a prospective biomarker for early brain injury in patients with aneurysmal …

Introduction Preclinical studies provided a strong rationale for a pathophysiological link
between cell-free hemoglobin in the cerebrospinal fluid (CSF-Hb) and secondary brain …

Object Experimental studies have demonstrated the crucial role of posthemorrhagic
erythrocyte catabolism in the pathogenesis of subarachnoid hemorrhage (SAH). The authors …

Objective Anemia predicts poor outcome following aneurysmal subarachnoid hemorrhage
(SAH). We hypothesized that this association would be stronger among patients with more …

Hemoglobin (HGB), a potent spasmogen, may cause irreversible damage to the brain after
aneurysm rupture. However, there is no clinical evidence to reveal the relationship between …

Background Cerebral vasospasm is a major contributor to disability and mortality after
aneurysmal subarachnoid hemorrhage. Oxidation of cell-free hemoglobin plays an integral …

Introduction Anemia is common after subarachnoid hemorrhage (SAH) and may exacerbate
the reduction in oxygen delivery that underlies delayed cerebral ischemia. Fall in …

Delayed ischemic neurological deficit (DIND) is a major driver of adverse outcomes in
patients with aneurysmal subarachnoid hemorrhage (aSAH), defining an unmet need for …