Mechanisms mediating the impact of maternal obesity on offspring hypothalamic development and later function
IC Furigo, L Dearden - Frontiers in endocrinology, 2022 - frontiersin.org
As obesity rates have risen around the world, so to have pregnancies complicated by
maternal obesity. Obesity during pregnancy is not only associated with negative health …
maternal obesity. Obesity during pregnancy is not only associated with negative health …
[HTML][HTML] Maternal obesity causes fetal hypothalamic insulin resistance and disrupts development of hypothalamic feeding pathways
L Dearden, S Buller, IC Furigo… - Molecular …, 2020 - Elsevier
Objective Perinatal exposure to maternal obesity results in predisposition of offspring to
develop obesity later in life. Increased weight gain in offspring exposed to maternal obesity …
develop obesity later in life. Increased weight gain in offspring exposed to maternal obesity …
Early life influences on obesity risk: maternal overnutrition and programming of obesity
MJ Morris - Expert Review of Endocrinology & Metabolism, 2009 - Taylor & Francis
While adult lifestyle factors undoubtedly contribute to the incidence of obesity and its
attendant disorders, mounting evidence suggests that programming of obesity may occur …
attendant disorders, mounting evidence suggests that programming of obesity may occur …
Female and male C57BL/6J offspring exposed to maternal obesogenic diet develop altered hypothalamic energy metabolism in adulthood
D Kulhanek, JE Abrahante Llorens… - American Journal …, 2022 - journals.physiology.org
Maternal obesity is exceedingly common and strongly linked to offspring obesity and
metabolic disease. Hypothalamic function is critical to obesity development. Hypothalamic …
metabolic disease. Hypothalamic function is critical to obesity development. Hypothalamic …
Emerging role of hypothalamus in the metabolic regulation in the offspring of maternal obesity
J Zhang, S Li, X Luo, C Zhang - Frontiers in Nutrition, 2023 - frontiersin.org
Maternal obesity has a significant impact on the metabolism of offspring both in childhood
and adulthood. The metabolic regulation of offspring is influenced by the intrauterine …
and adulthood. The metabolic regulation of offspring is influenced by the intrauterine …
Effects of neonatal programming on hypothalamic mechanisms controlling energy balance
C Contreras, MG Novelle, R Leis… - Hormone and …, 2013 - thieme-connect.com
The prevalence of overweight and obesity in most developed countries has markedly
increased during the last decades. In addition to genetic, hormonal, and metabolic …
increased during the last decades. In addition to genetic, hormonal, and metabolic …
Persistent influence of maternal obesity on offspring health: Mechanisms from animal models and clinical studies
The consequences of excessive maternal weight and adiposity at conception for the
offspring are now well recognized. Maternal obesity increases the risk of overweight and …
offspring are now well recognized. Maternal obesity increases the risk of overweight and …
Maternal obesity: lifelong metabolic outcomes for offspring from poor developmental trajectories during the perinatal period
E Zambrano, C Ibáñez, PM Martinez-Samayoa… - Archives of medical …, 2016 - Elsevier
The prevalence of obesity in women of reproductive age is increasing in developed and
developing countries around the world. Human and animal studies indicate that maternal …
developing countries around the world. Human and animal studies indicate that maternal …
The Endocrine–Metabolic Axis Regulation in Offspring Exposed to Maternal Obesity—Cause or Consequence in Metabolic Disease Programming?
Obesity incidence is rising worldwide, including women of reproductive age, contributing to
increased gestations in which Maternal Obesity (MO) occurs. Offspring born to obese …
increased gestations in which Maternal Obesity (MO) occurs. Offspring born to obese …
Neurodevelopmental programming of adiposity: contributions to obesity risk
AA Skowronski, RL Leibel, CA LeDuc - Endocrine Reviews, 2024 - academic.oup.com
This review analyzes the published evidence regarding maternal factors that influence the
developmental programming of long-term adiposity in humans and animals via the central …
developmental programming of long-term adiposity in humans and animals via the central …