[PDF][PDF] Marine Antineoplastic Templates: Clinical Trials (I–III) and Motifs Carried via Antibodies to Target Specific Cancerous Tissues

AN El-Shorbagi, S Chaudhary, A Chaudhary… - Biomed …, 2022 - researchgate.net
Aquatic environment is one of the important sources of active agents that own diverse
biological properties. Metabolites from these sources are considered as alternate source to …

The “utility” of highly toxic marine-sourced compounds

DJ Newman - Marine drugs, 2019 - mdpi.com
Currently a few compounds isolated from marine sources have become drugs, mainly
directed towards cancer and pain. Compounds from marine sources have exquisite …

Antibody-drug conjugates containing payloads from marine origin

I Cheng-Sánchez, F Moya-Utrera, C Porras-Alcalá… - Marine Drugs, 2022 - mdpi.com
Antibody-drug conjugates (ADCs) are an important class of therapeutics for the treatment of
cancer. Structurally, an ADC comprises an antibody, which serves as the delivery system, a …

Marine‐derived Pharmaceuticals for Oncotherapy: Clinical Trial and FDA‐approved Compounds

RH Prabhu, VB Patravale - Encyclopedia of Marine …, 2020 - Wiley Online Library
There is an increasing need for novel oncotherapeutics to treat cancer and to overcome
emerging resistance to current cancer treatment regimen. The marine environment …

From life in the sea to the clinic: The marine drugs approved and under clinical trial

E Cappello, P Nieri - Life, 2021 - mdpi.com
In the last decades Blue Growth policy in european and non-european countries produced a
great impulse in applied marine sciences, comprehending the research of new bioactive …

Anticancer drugs discovery and development from marine organisms

C Chakraborty, CH Hsu, ZH Wen… - Current topics in …, 2009 - ingentaconnect.com
The chemical and biological diversity of the different marine evolutionary group is endless
and therefore, this is an amazing resource for the discovery of new anticancer drugs …

Current status of marine-derived compounds as warheads in anti-tumor drug candidates

DJ Newman, GM Cragg - Marine Drugs, 2017 - mdpi.com
In this review, we have attempted to describe all of the antibody–drug conjugates using a
marine-derived compound as the “warhead”, that are currently in clinical trials as listed in the …

From seabed to bedside: A review on promising marine anticancer compounds

E Wang, MA Sorolla, PD Gopal Krishnan, A Sorolla - Biomolecules, 2020 - mdpi.com
The marine environment represents an outstanding source of antitumoral compounds and,
at the same time, remains highly unexplored. Organisms living in the sea synthesize a wide …

Marine drugs for cancer: Surfacing biotechnological innovations from the oceans

PC Jimenez, DV Wilke, LV Costa-Lotufo - Clinics, 2018 - SciELO Brasil
This review will discuss the contributions of marine natural molecules, a source only recently
found to have pharmaceutical prospects, to the development of anticancer drugs. Of the …

Marine invertebrate metabolites with anticancer activities: Solutions to the “supply problem”

NGM Gomes, R Dasari, S Chandra, R Kiss… - Marine drugs, 2016 - mdpi.com
Marine invertebrates provide a rich source of metabolites with anticancer activities and
several marine-derived agents have been approved for the treatment of cancer. However …