Cryptococcus neoformans and C. gattii, the etiologic agents of cryptococcosis, cause over
100,000 deaths worldwide every year, yet no cryptococcal vaccine has progressed to …

Cryptococcosis is a fungal disease caused by multiple Cryptococcus serotypes; particularly
C. neoformans (serotypes A and D) and C. gattii (serotypes B and C). To date, there is no …

Cryptococcus neoformans is an opportunistic fungal pathogen that causes life-threatening
pneumonia and meningoencephalitis in immune compromised individuals. Previous studies …

Vaccines are one of the greatest medical accomplishments to date, yet no fungal vaccines
are currently available in humans mainly because opportunistic mycoses generally occur …

Cryptococcus neoformans is a major opportunistic fungal pathogen that causes fatal
meningoencephalitis in immunocompromised individuals and is responsible for a large …

Tumor necrosis factor alpha (TNF-α) plays a critical role in the control of cryptococcal
infection, and its insufficiency promotes cryptococcal persistence. To explore the therapeutic …

Cryptococcus neoformans is an opportunistic fungal pathogen that threatens individuals with
impaired cell-mediated immunity (CMI). Presently, there are no standardized vaccines …

Cryptococcus neoformans, the etiological agent of cryptococcosis, is an occasional
opportunistic fungal pathogen of immune competent individuals. However, it is a relatively …

Cryptococcus gattii is a fungal pathogen that can cause life-threatening respiratory and
disseminated infections in immune-competent and immune-suppressed individuals …

Cryptococcus neoformans and C. gattii, the predominant etiological agents of
cryptococcosis, can cause life-threatening infections of the central nervous system in …