The Yin and Yang of myeloid derived suppressor cells

S Budhwar, P Verma, R Verma, S Rai… - Frontiers in …, 2018 - frontiersin.org
In recent years, most of our knowledge about myeloid derived suppressor cells (MDSCs)
has come from cancer studies, which depicts Yin side of MDSCs. In cancer, inherent …

Landscape of myeloid-derived suppressor cell in tumor immunotherapy

Z Hao, R Li, Y Wang, S Li, Z Hong, Z Han - Biomarker Research, 2021 - Springer
Myeloid-derived suppressor cells (MDSC) are a group of immature cells that produced by
emergency myelopoiesis. Emerging evidences have identified the vital role of MDSC in …

Understanding the differentiation, expansion, recruitment and suppressive activities of myeloid-derived suppressor cells in cancers

HX Lim, TS Kim, CL Poh - International journal of molecular sciences, 2020 - mdpi.com
There has been a great interest in myeloid-derived suppressor cells (MDSCs) due to their
biological functions in tumor-mediated immune escape by suppressing antitumor immune …

Myeloid-derived suppressor cells in cancer immunotherapy-clinical perspectives

K Mortezaee - Life sciences, 2021 - Elsevier
Myeloid-derived suppressor cells (MDSCs) are heterogeneous and poorly mature cells of
innate immunity that their population is increased substantially in cancer patients. MDSCs …

Negative regulation of myeloid-derived suppressor cells in cancer

P Qu, KC Boelte, PC Lin - Immunological investigations, 2012 - Taylor & Francis
Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of immature
myeloid cells with suppressive function on immune response. In this review, we discuss …

Myeloid-derived suppressor cells as immunosuppressive regulators and therapeutic targets in cancer

K Li, H Shi, B Zhang, X Ou, Q Ma, Y Chen… - Signal transduction and …, 2021 - nature.com
Myeloid-derived suppressor cells (MDSCs) are a heterogenic population of immature
myeloid cells with immunosuppressive effects, which undergo massive expansion during …

[HTML][HTML] Myeloid-derived suppressor cells in tumors: from mechanisms to antigen specificity and microenvironmental regulation

Y Yang, C Li, T Liu, X Dai, AV Bazhin - Frontiers in immunology, 2020 - frontiersin.org
Among the various immunological and non-immunological tumor-promoting activities of
myeloid-derived suppressor cells (MDSCs), their immunosuppressive capacity remains a …

Recent advances in myeloid-derived suppressor cell biology

MM Yaseen, NM Abuharfeil, H Darmani, A Daoud - Frontiers of Medicine, 2021 - Springer
In recent years, studying the role of myeloid-derived suppressor cells (MDSCs) in many
pathological inflammatory conditions has become a very active research area. Although the …

Myeloid-derived suppressor cells in hematological malignancies: friends or foes

M Lv, K Wang, X Huang - Journal of Hematology & Oncology, 2019 - Springer
Myeloid-derived suppressor cells (MDSCs) are newly identified immature myeloid cells that
are characterized by the ability to suppress immune responses and expand during cancer …

Myeloid‐derived suppressor cells and tumor: Current knowledge and future perspectives

E Safari, S Ghorghanlu… - Journal of Cellular …, 2019 - Wiley Online Library
The immunosuppressive features of tumor lesions participate not only as one of the major
players inducing cancer progression but also a big challenge for effective immunotherapy. It …