Myeloid-derived suppressor cells (MDSCs) represent an important class of
immunoregulatory cells that can be activated to suppress T cell functions. These MDSCs can …

Tumor cells use several mechanisms such as soluble immune modulators or suppressive
immune cells to evade from anti-tumor responses. Immunomodulatory cytokines, such as …

Chronic inflammation, typical of various diseases including cancer, is a “silent bomb within
the body,” leading to complications that are only evident in most cases upon their …

Myeloid derived suppressor cells (MDSC) have been described as a heterogeneous cell
population with potent immune suppressor function in mice. Limited data are available on …

Evading immune destruction is a hallmark of cancer. Myeloid‐derived suppressor cells
(MDSCs), a heterogeneous population of myeloid immune cells, are thought to foster the …

Myeloid-derived suppressor cells (MDSCs) are one of the major negative regulators in tumor
microenvironment (TME) due to their potent immunosuppressive capacity. MDSCs are the …

Immune evasion is a characteristic of most human malignancies and is induced via various
mechanisms. Immunosuppressive cells, including myeloid‐derived suppressor cells …

Abstract Myeloid Derived Suppressor Cells (MDSC) are a heterogeneous population of
immature myeloid cells that are increased in states of cancer, inflammation and infection. In …

Accumulation of pathologically activated immature myeloid cells with potent immune-
suppressive activity is one of the major immunological hallmarks of cancer. In recent years, it …

Lung cancer (LC) is the leading cause of cancer-related death worldwide due to its late
diagnosis and poor outcomes. As has been found for other types of tumors, there is …