Alcohol, its absorption, distribution, metabolism, and excretion in the body and pharmacokinetic calculations

AW Jones - Wiley Interdisciplinary Reviews: Forensic Science, 2019 - Wiley Online Library
The ethanol contained in alcoholic beverages is rapidly absorbed from the gastrointestinal
tract and the maximum blood‐alcohol concentration (BAC) is usually reached between 10 …

[PDF][PDF] Pharmacokinetics of ethanol–issues of forensic importance

AW Jones - Forensic Sci Rev, 2011 - researchgate.net
A reliable method for the quantitative analysis of ethanol in microvolumes (50–100 μL) of
blood became available in 1922, making it possible to investigate the absorption …

Role of variability in explaining ethanol pharmacokinetics: research and forensic applications

Å Norberg, AW Jones, RG Hahn… - Clinical pharmacokinetics, 2003 - Springer
Variability in the rate and extent of absorption, distribution and elimination of ethanol has
important ramifications in clinical and legal medicine. The speed of absorption of ethanol …

Evidence-based survey of the elimination rates of ethanol from blood with applications in forensic casework

AW Jones - Forensic science international, 2010 - Elsevier
Reliable information about the elimination rate of alcohol (ethanol) from blood is often
needed in forensic science and legal medicine when alcohol-related crimes, such as …

Pharmacokinetics of ethanol: Absorption, distribution, and elimination.

H Kalant - 1996 - psycnet.apa.org
Abstract pharmacokinetics has been a central part of the study of the biology of alcohol and
alcoholism since the beginning of systematic scientific research in this field/precise …

Disappearance rate of ethanol from the blood of human subjects: implications in forensic toxicology

AW Jones - Journal of forensic sciences, 1993 - asmedigitalcollection.asme.org
This article outlines major developments in knowledge about the human metabolism of
ethanol. The results of a large number of controlled experiments aimed at measuring the …

A kinetic model describing the pharmacokinetics of ethyl glucuronide in humans

P Droenner, G Schmitt, R Aderjan, H Zimmer - Forensic science …, 2002 - Elsevier
The glucuronide conjugation is a minor pathway of ethanol metabolism. The determination
of ethyl glucuronide (EG) in serum and urine has gained importance in forensic and other …

A pharmacokinetic study of ethyl glucuronide in blood and urine: applications to forensic toxicology

G Høiseth, JP Bernard, R Karinen, L Johnsen… - Forensic science …, 2007 - Elsevier
This pharmacokinetic study investigated the kinetics of ethanol and its metabolite ethyl
glucuronide (EtG) in blood and urine during the whole time course of absorption and …

An overview of alcohol testing and interpretation in the 21st century

AT Kelly, A Mozayani - Journal of pharmacy practice, 2012 - journals.sagepub.com
Ethanol analysis is the most commonly carried out drug testing in a forensic toxicology
laboratory. Determination of blood alcohol concentration (BAC) is needed in a multitude of …

Direct measurement of alcohol and its metabolites

R Swift - Addiction, 2003 - Wiley Online Library
Background Ethanol can be easily and accurately measured in body fluids or vapours by
several chemical and enzymatic methods. However, the persistence of ethanol in the body is …