Cell-penetrating peptides (CPPs) have been previously shown to be powerful transport
vector tools for the intracellular delivery of a large variety of cargoes through the cell …

The process of introducing drugs into cells has always proved a major challenge for
research scientists and for the pharmaceutical industry. The cell membrane is selectively …

Cancer has become one of the leading causes of mortality globally. The major challenges of
conventional cancer therapy are the failure of most chemotherapeutic agents to accumulate …

One of the major challenges for new therapeutics molecules to enter the clinic remains
improving their bioavailability and cellular uptake. Therefore, delivery has become a key …

Despite continuing advances in the development of biomacromolecules for therapeutic
purposes, successful application of these often large and hydrophilic molecules has been …

An important hurdle for the intracellular delivery of large cargo is the cellular membrane,
which protects the cell from exogenous substances. Cell-penetrating peptides (CPPs) can …

Introduction: Cell-penetrating peptides (CPP) offer versatile tools for the field of drug delivery
and development of macromolecular therapeutics. These tools have matured into …

The cell membrane is a highly selective barrier. This limits the cellular uptake of molecules
including DNA, oligonucleotides, peptides and proteins used as therapeutic agents …

The penetration of polar or badly soluble compounds through a cell membrane into live cells
requires mechanical support or chemical helpers. Cell‐penetrating peptides (CPPs) are very …

Cell-penetrating peptides (CPPs) have been discovered to deliver chemical drugs, nucleic
acids, and macromolecules to permeate cell membranes, creating a novel route for …