Vertebrate skeletal myofibers are heterogeneous with respect to their metabolic, contractile
and morphological properties. To better understand skeletal myofiber diversity and plasticity …

Background Skeletal muscle is a complex, versatile tissue composed of a variety of
functionally diverse fiber types. Although the biochemical, structural and functional …

Adult skeletal muscle fibres are classified as type 1, 2A, 2X, and 2B. These classifications
are based on the expression of the dominant myosin heavy chain isoform. Muscle fibre …

We investigated fast and slow muscle fiber transcriptome exercise dynamics among three
groups of men: lifelong exercisers (LLE, n= 8, 74±1 yr), old healthy nonexercisers (OH, n= 9 …

Muscle fiber cross-sectional area (CSA) and proportion of different fiber types are important
determinants of muscle function and overall metabolism. Genetic variation plays a …

Background Individual skeletal muscles have evolved to perform specific tasks based on
their molecular composition. In general, muscle fibers are characterized as either fast-twitch …

We applied K-means cluster analysis to test the hypothesis that muscle-specific factors
known to modulate protein synthesis and satellite cell activity would be differentially …

Skeletal muscle is an inherently heterogenous tissue comprised primarily of myofibers,
which are historically classified into three distinct fiber types in humans: one “slow”(type 1) …

Mammalian skeletal muscles are composed of two major fibre types (I and II) that differ in
terms of size, metabolism and contractile properties. In general, slow‐twitch type I fibres are …

Aging and obesity pose significant threats to public health and are major contributors to
muscle atrophy. The trends in muscle fiber types under these conditions and the …