The ever-increasing prevalence of noncommunicable diseases (NCDs) represents a major
public health burden worldwide. The most common form of NCD is metabolic diseases …

The metabolism of glucose and lipids is essential for energy production in the body, and
dysregulation of the metabolic pathways of these molecules is implicated in various acute …

Protein posttranslational modifications (PTMs) refer to the breaking or generation of covalent
bonds on the backbones or amino acid side chains of proteins and expand the diversity of …

Cardiovascular disease (CVD) has become a leading cause of mortality and morbidity
globally, making it an urgent concern. Although some studies have been performed on CVD …

Modern drug design aims to discover novel lead compounds with attractable chemical
profiles to enable further exploration of the intersection of chemical space and biological …

Post-translational modifications (PTMs) alter protein structure, function, and localization and
play a pivotal role in physiological and pathophysiological conditions. Many PTMs arise from …

Cardiovascular diseases (CVDs) such as atherosclerosis, myocardial remodeling,
myocardial ischemia-reperfusion (I/R) injury, heart failure, and oxidative stress are among …

Posttranslational modifications (PTMs) modulate protein function in most eukaryotes and
have a ubiquitous role in diverse range of cellular functions. Identification, characterization …

Protein post-translational modifications (PTMs), which are usually enzymatically catalyzed,
are major regulators of protein activity and involved in almost all celluar processes …

The development and application of traditional drugs represented by small molecule
chemical drugs and biological agents, especially inhibitors, have become the mainstream …