[HTML][HTML] Cisplatin-loaded polybutylcyanoacrylate nanoparticles with improved properties as an anticancer agent

SE Alavi, S Muflih Al Harthi… - International Journal of …, 2019 - mdpi.com
This study aims to improve the cytotoxicity and potency of cisplatin-loaded
polybutylcyanoacrylate (PBCA) nanoparticles (NPs) for the treatment of lung cancer through …

[HTML][HTML] Investigating the properties and cytotoxicity of cisplatin-loaded nano-polybutylcyanoacrylate on breast cancer cells

A Gorgzadeh, A Hheidari, P Ghanbarikondori… - Asian Pacific Journal of …, 2023 - waocp.com
Background: This study aimed to develop a novel drug formulation using
polybutylcyanoacrylate (PBCA) nanoparticles to deliver cisplatin, a commonly used …

[HTML][HTML] Preparation, characterization, and evaluation of cisplatin-loaded polybutylcyanoacrylate nanoparticles with improved in vitro and in vivo anticancer activities

M Ghaferi, S Amari, B Vivek Mohrir, A Raza… - Pharmaceuticals, 2020 - mdpi.com
This study aimed to evaluate the therapeutic efficacy of the cisplatin encapsulated into
polybutylcyanoacrylate (PBCA) nanoparticles for the treatment of kidney cancer. The …

Enhancing anti-cancer efficacy of carboplatin by PEGylated poly (butyl cyanoacrylate) nano-particles

M Hassanzadeganroudsari, A Heydarinasab… - Journal of Drug Delivery …, 2019 - Elsevier
Nano-drug delivery holds great potential to enhance the efficacy of carboplatin. This study
focused on cytotoxicity, in vitro drug release and characterization of poly (butyl …

Efficacy of Cisplatin-loaded polybutyl cyanoacrylate nanoparticles on the glioblastoma

H Ebrahimi Shahmabadi, F Movahedi… - Tumor Biology, 2014 - Springer
Glioblastoma is known as one of the most aggressive human cancers. To gain access of the
brain, therapeutic agents must overcome blood–brain barrier (BBB). In this study, Cisplatin …

Drug delivery of cisplatin to breast cancer by polybutylcyanoacrylate nanoparticles

M Koohi Moftakhari Esfahani, SE Alavi… - Advances in Polymer …, 2018 - Wiley Online Library
Breast cancer is the most common cancer and the second cause of cancer‐related death in
women worldwide. Chemotherapy of disease is impeded by subsequent relapse and …

Enhanced antitumoral activity of doxorubicin against lung cancer cells using biodegradable poly (butylcyanoacrylate) nanoparticles

C Melguizo, L Cabeza, J Prados, R Ortiz… - Drug design …, 2015 - Taylor & Francis
Doxorubicin (Dox) is widely used for the combined chemotherapy of solid tumors. However,
the use of these drug associations in lung cancer has low antitumor efficacy. To improve its …

Preparation and physicochemical characterization of novel chlorambucil-loaded nanoparticles of poly (butylcyanoacrylate)

GG Yordanov, ZA Bedzhova, CD Dushkin - Colloid and Polymer Science, 2010 - Springer
The aim of the present study is the preparation and physicochemical characterization of
chlorambucil-loaded poly (butylcyanoacrylate) nanoparticles. Chlorambucil is a lipophilic …

Engineering of hybrid anticancer drug-loaded polymeric nanoparticles delivery system for the treatment and care of lung cancer therapy

Y Zhao, K Liu, J Li, J Liao, L Ma - Drug Delivery, 2021 - Taylor & Francis
Chemotherapy with combination drugs has become one of the most commonly used cancer
prevention treatments, with positive clinical results. The goal of this study was to develop …

Poly (ethyl 2-cyanoacrylate) nanoparticles (PECA-NPs) as possible agents in tumor treatment

A Obinu, G Rassu, P Corona, M Maestri, F Riva… - Colloids and Surfaces B …, 2019 - Elsevier
Tumor eradication has many challenges due to the difficulty of selectively delivering
anticancer drugs to malignant cells avoiding contact with healthy tissues/organs. The …