Context: Paclitaxel (PTX) and carboplatin (CBP) are widely used for the combined
chemotherapy of non-small cell lung cancer (NSCLC). However, the development of …

Despite significant advances in cancer therapy, chemotherapeutic agents are still the main
types of drugs used to treat cancer patients. 5-Fluorouracil (5-FU) is the first-line treatment in …

The purpose of this study was to develop a nanocarrier system for codelivery of paclitaxel
(PTX) and piperlongumine (PL) and investigate the therapeutic potential of improving …

Cancer is recognized as one of the world's deadliest diseases, with more than 10 million
new cases each year. Over the past 2 decades, several studies have been performed on …

In this study, zinc phthalocyanine (ZnPc) was loaded onto poly-ɛ-caprolactone (PCL)
nanoparticles (NPs) using a solvent emulsification–evaporation method. The process yield …

Multi-drug resistance (MDR) is the major hindrance towards the successful treatment of
malignant lung cancer. The aim of this study was to develop a novel nanoparticle co-loaded …

Polybutylcyanoacrylate (PBCA) nanoparticles coated with polysorbate-80 have been
extensively studied for delivery of drugs into the animal models; however, 1% polysorbate …

Chemotherapy is a common treatment technique that uses chemical drugs to kill cancer
cells. This technique affects normal healthy tissues being unspecific and has toxic adverse …

The poor selectivity of chemotherapeutics for cancer treatment may lead to dose-limiting
side effects that compromise clinical outcomes. To solve the problem, surface-functionalized …

The study aimed to prepare imatinib mesylate-loaded polybutylcyanoacrylate (PBCA)
nanoparticles and evaluate their efficacy on leukemia cell line K562. The formulation was …