Background Although cisplatin is extensively used in the clinical field, its intrinsic toxicity
limits its clinical use. We investigated nanoparticle formations of poly (acrylic acid-co-methyl …

Chemotherapy-based treatment for cancer has made great progress in the past decades.
However, there is still a big challenge for the treatment of lung cancer. Herein, a …

Background Liver targeting drug delivery systems can improve the curative effects and
relieve the cytotoxicity of the chemotherapy drugs in the treatment of liver diseases …

Purpose Co-delivery of two or more drugs into the same cancer cells or tissues in the same
nanocarriers provides a new paradigm in cancer treatment. In this study, two kinds of …

Carboplatin (CP), a platinum analog, is one of the most widely used chemotherapeutic
agents in the treatment of colorectal cancer. Although platinum-based drugs are quite …

For effective therapy for glioma, it is essential for chemotherapeutics to pass the blood-brain
barrier to target glioma cells with little side effects to surrounding normal cells. In this study …

For non-small cell lung cancer (NSCLC) treatment, a BCS class II drug, Gefitinib, was widely
used. Due to poor bioavailability, uncontrollable drug release, Gefitinib witnessed side …

Functionalized amphiphilic polymers consisting of hydrophilic poly (ethylene glycol) pendant
groups and a hydrophobic poly (epichlorohydrin) backbone can spontaneously self …

Co-delivery of multiple drugs with complementary anticancer mechanisms by nano-carriers
offers an effective strategy to treat cancer. The combination of drugs with pro-apoptotic and …

Combinations of two potent chemotherapeutic drugs are often used to treat early stage lung
cancer. To enhance the efficiency of the treatment, a combinational co-drug delivery system …