Background Although estrogen (ERα/ERβ), progesterone (PGR), and androgen (AR)
receptors are pathologically altered in colorectal cancer (CRC), their simultaneous …

We reported that high estrogen receptor beta (ERβ) expression is independently associated
with better prognosis in female colorectal cancer (CRC) patients. However, estrogen …

Although ovarian sex steroids could have protective roles against colorectal cancer (CRC) in
women, little is currently known about their potential anti-tumorigenic effects in men. Hence …

Background: Previous studies suggest that sex steroids influence colorectal cancer (CRC)
carcinogenesis. The oestrogen receptor β (ERβ) is the predominantly expressed ER in the …

Objective To understand the relationship between steroid hormones synthesized by the
gonads and colorectal cancer as well as its tumor microenvironment, in the expectation of …

Background The oestrogen receptor beta (ERβ) is the predominant oestrogen receptor in
the normal colon mucosa and has been reported to exert anti-proliferative and pro-apoptotic …

Several epidemiological studies have reported that the use of female sex steroid hormones
could reduce the risk of colon cancer (CRC). This review summarizes the available data …

Dysregulation of estrogen related pathways is implicated colorectal cancer (CRC)
development. However, significance of intratissue concentration of estrone (E1) and 17β …

Colorectal cancer (CRC) is the second cause of cancer-related death in both sexes
worldwide. As pre-menopausal women are less likely to develop CRC compared to age …

Colorectal cancer (CRC) is one of the most common types of malignancy with high morbidity
and mortality rates worldwide. This biologically heterogeneous disease results in diverse …