Phosphate is a key uremic toxin associated with adverse outcomes. As chronic kidney
disease (CKD) progresses, the kidney capacity to excrete excess dietary phosphate …

Hyperphosphatemia is a mineral bone-disease that increases cardiovascular complications
and all-cause mortality in chronic kidney disease (CKD) patients. Oral phosphate binders …

Gut microbiome, parathyroid hormone, and bone : Current Opinion in Nephrology and
Hypertension Gut microbiome, parathyroid hormone, and bone : Current Opinion in Nephrology …

Exposed surfaces of mammals are colonized with 100 trillion indigenous bacteria, fungi, and
viruses, creating a diverse ecosystem known as the human microbiome. The gut microbiome …

Bone loss is a frequent but not universal complication of hyperparathyroidism. Using
antibiotic-treated or germ-free mice, we show that parathyroid hormone (PTH) only caused …

Parathyroid hormone (PTH) is a critical regulator of skeletal development that promotes both
bone formation and bone resorption. Using microbiota depletion by wide-spectrum …

1Division of Endocrinology, Metabolism and Lipids, Department of Medicine, Emory
University, Atlanta, GA, 2Emory Microbiome Center, Emory University, Atlanta, GA. 3Atlanta …

Recent studies have shown that patients with kidney stone disease, and particularly calcium
oxalate nephrolithiasis, exhibit dysbiosis in their fecal and urinary microbiota compared with …

Chronic kidney disease (CKD)–mineral and bone disorder is associated with diverse
metabolic and endocrine disturbances that ultimately may contribute to further loss of kidney …

Osteoporosis is the most common metabolic skeletal disease. It is characterized by the
deterioration of the skeletal microarchitecture and bone loss, leading to ostealgia, and even …