[HTML][HTML] Pharmacologically augmented S-nitrosylated hemoglobin improves recovery from murine subarachnoid hemorrhage
H Sheng, JD Reynolds, RL Auten, IT Demchenko… - Stroke, 2011 - journals.lww.com
Background and Purpose—S-nitrosylated hemoglobin (S-nitrosohemoglobin) has been
implicated in the delivery of O 2 to tissues through the regulation of microvascular blood …
implicated in the delivery of O 2 to tissues through the regulation of microvascular blood …
Hypervolemic-hemodilution during cerebral ischemia in rats: effect of diaspirin cross-linked hemoglobin (DCLHb) on neurologic outcome and infarct volume
DJ Cole, JC Drummond, PM Patel… - Journal of …, 1997 - journals.lww.com
In a rat model of middle cerebral artery occlusion (MCAo) and reperfusion (120 min),
previous studies have demonstrated that hemodilution with molecular hemoglobin …
previous studies have demonstrated that hemodilution with molecular hemoglobin …
Building the case for targeting the secondary injury after intracerebral hemorrhage: slowly but surely
M Selim - Stroke, 2022 - Am Heart Assoc
The hemolysis of red blood cells after intracerebral hemorrhage (ICH) releases hemoglobin
degradation products and iron, which precipitate a cascade of events, including free …
degradation products and iron, which precipitate a cascade of events, including free …
Diaspirin cross-linked hemoglobin resuscitation improves cerebral perfusion after head injury and shock
JE Chappell, WJ McBride… - Journal of Trauma and …, 1996 - journals.lww.com
Background Shock associated with traumatic brain injury (TBI) doubles the mortality of TBI
alone by inducing a secondary ischemic injury. Rapid correction of cerebral perfusion …
alone by inducing a secondary ischemic injury. Rapid correction of cerebral perfusion …
Haptoglobin treatment for aneurysmal subarachnoid hemorrhage: review and expert consensus on clinical translation
Aneurysmal subarachnoid hemorrhage (aSAH) is a devastating form of stroke frequently
affecting young to middle-aged adults, with an unmet need to improve outcome. This special …
affecting young to middle-aged adults, with an unmet need to improve outcome. This special …
Protocolized brain oxygen optimization in subarachnoid hemorrhage
V Rass, D Solari, B Ianosi, M Gaasch, M Kofler… - Neurocritical care, 2019 - Springer
Background Brain tissue hypoxia (P bt O 2< 20 mmHg) is common after subarachnoid
hemorrhage (SAH) and associated with poor outcome. Recent data suggest that brain …
hemorrhage (SAH) and associated with poor outcome. Recent data suggest that brain …
Association between perihematomal perfusion and intracerebral hemorrhage outcome
Background The prognostic impact of perihematomal hypoperfusion in patients with acute
intracerebral hemorrhage (ICH) remains unclear. We tested the hypothesis that …
intracerebral hemorrhage (ICH) remains unclear. We tested the hypothesis that …
Red blood cell transfusion increases cerebral oxygen delivery in anemic patients with subarachnoid hemorrhage
Background and Purpose—Anemia is common after subarachnoid hemorrhage and may
exacerbate the reduction in oxygen delivery (DO2) underlying delayed cerebral ischemia …
exacerbate the reduction in oxygen delivery (DO2) underlying delayed cerebral ischemia …
Polynitroxylated pegylated hemoglobin: a novel neuroprotective hemoglobin for acute volume-limited fluid resuscitation after combined traumatic brain injury and …
DK Shellington, L Du, X Wu, J Exo, V Vagni… - Critical care …, 2011 - journals.lww.com
Objective: Resuscitation of hemorrhagic hypotension after traumatic brain injury is
challenging. A hemoglobin-based oxygen carrier may offer advantages. The novel …
challenging. A hemoglobin-based oxygen carrier may offer advantages. The novel …
Vasoactivity of bovine polymerized hemoglobin (HBOC-201) in swine with traumatic hemorrhagic shock with and without brain injury
J Rice, N Philbin, M Handrigan, C Hall… - Journal of Trauma …, 2006 - journals.lww.com
Background: We previously reported that bovine polymerized hemoglobin (HBOC-201)
improved outcome in swine with hemorrhagic shock (HS) with and without traumatic brain …
improved outcome in swine with hemorrhagic shock (HS) with and without traumatic brain …