Although the incidence is declining, subarachnoid hemorrhage (SAH) continues to exact a
substantial toll on society, with an estimated 20,000 aneurysmal SAHs (aSAHs) a year in the …

Background The objective of this study was to investigate the relationship between cardiac
index (CI) response to a fluid challenge and changes in brain tissue oxygen pressure (PbtO …

Background Endovascular thrombectomy (EVT) is highly effective but may also lead to
hemorrhagic transformation (HT) and edema, which may be more pronounced in severe …

Background Fluid management in patients after subarachnoid hemorrhage (SAH) aims at
the optimization of cerebral blood flow and brain oxygenation. In this study, we investigated …

Introduction Several studies demonstrated that patients with low blood pressure upon
presentation with acute ischemic stroke have worse outcomes. Elevated mean arterial …

Introduction Anemia is common after subarachnoid hemorrhage (SAH) and may exacerbate
the reduction in oxygen delivery that underlies delayed cerebral ischemia. Fall in …

Object Critical reductions in oxygen delivery (DO 2) underlie the development of delayed
cerebral ischemia (DCI) after subarachnoid hemorrhage (SAH). If DO 2 is not promptly …

Secondary brain injury after aneurysmal subarachnoid hemorrhage (SAH-SBI) contributes to
poor outcomes in patients after rupture of an intracranial aneurysm. The lack of diagnostic …

Background This study investigated if cerebral blood flow (CBF) regulation by changes of
the arterial partial pressure of carbon dioxide (PaCO 2) can be used therapeutically to …

Background and Purpose—Delayed cerebral ischemia and infarction due to reduced CBF
remains the leading cause of poor outcome after aneurysmal subarachnoid hemorrhage …