Lipodystrophies, heterogeneous acquired or inherited disorders characterized by the
selective loss of adipose tissue, predispose affected patients to insulin resistance and its …

Purpose of review This article focuses on recent progress in understanding the genetics of
lipodystrophy syndromes, the pathophysiology of severe metabolic abnormalities caused by …

Selective loss of body fat is the hallmark of patients with lipodystrophies. Among genetic
lipodystrophies, fat loss is observed either from birth, as in congenital generalized …

Lipodystrophies are an immense group of genetic or acquired metabolic disorders that are
characterized by varying degrees of body fat loss and in some instances localized …

Lipodystrophies have been recognized since at least the nineteenth century and, despite
their rarity, tended to attract considerable medical attention because of the severity and …

Aim Lipodystrophy syndromes are rare heterogeneous disorders characterized by
deficiency of adipose tissue, usually a decrease in leptin levels and, frequently, severe …

Lipodystrophies are a heterogeneous group of congenital or acquired disorders,
characterized by partial or generalized loss of adipose tissue. Familial partial lipodystrophy …

The metabolic syndrome or insulin resistance syndrome is defined in relationship to
generalized or regional adiposity. The criteria for definition of ''metabolic syndrome''include …

Lipodystrophy syndromes are a heterogeneous group of diseases, characterized by
selective absence of adipose tissue. In one sense, these diseases are lipid-partitioning …

Objective To review the initial clinical manifestations of congenital and acquired
lipodystrophy syndromes, discuss novel classifications associated with genetic mutations …