mRNA-1273 or mRNA-Omicron boost in vaccinated macaques elicits comparable B cell expansion, neutralizing antibodies and protection against Omicron

M Gagne, JI Moliva, KE Foulds, SF Andrew, BJ Flynn… - BioRxiv, 2022 - biorxiv.org
SARS-CoV-2 Omicron is highly transmissible and has substantial resistance to antibody
neutralization following immunization with ancestral spike-matched vaccines. It is unclear …

SARS‐CoV‐2 Omicron and its current known unknowns: A narrative review

TTB Le, T Vasanthakumaran… - Reviews in Medical …, 2023 - Wiley Online Library
The emergence of the SARS‐CoV‐2 Omicron variant (B. 1.1. 529) has created great global
distress. This variant of concern shows multiple sublineages, importantly B. 1.1. 529.1 (BA …

Cross-neutralization of Omicron BA. 1 against BA. 2 and BA. 3 SARS-CoV-2

J Zou, C Kurhade, H Xia, M Liu, X Xie, P Ren… - Nature …, 2022 - nature.com
Abstract The Omicron SARS-CoV-2 has several distinct sublineages, among which
sublineage BA. 1 is responsible for the initial Omicron surge and is now being replaced by …

Disease profile and plasma neutralizing activity of post-vaccination Omicron BA. 1 infection in Tianjin, China: a retrospective study

H Zheng, Y Cao, X Chen, F Wang, Y Hu, W Song… - Cell research, 2022 - nature.com
Dear Editor, SARS-CoV-2 Omicron variant BA. 1 first emerged on the Chinese mainland on
January 8, 2022, in Tianjin and caused a large wave of infections. 1 Four rounds of mass …

Omicron-specific mRNA vaccine induced potent neutralizing antibody against Omicron but not other SARS-CoV-2 variants

IJ Lee, CP Sun, PY Wu, YH Lan, IH Wang, WC Liu… - BioRxiv, 2022 - biorxiv.org
The emerging SARS-CoV-2 variants of concern (VOC) harbor mutations associated with
increasing transmission and immune escape, hence undermine the effectiveness of current …

Antigenic mapping of emerging SARS-CoV-2 omicron variants BM. 1.1. 1, BQ. 1.1, and XBB. 1

AZ Mykytyn, ME Rosu, A Kok, M Rissmann… - The Lancet …, 2023 - thelancet.com
Novel SARS-CoV-2 omicron variants, including BM. 1.1. 1, BQ. 1.1, and XBB. 1, continue to
emerge at an unprecedented rate, evading preexisting immunity from vaccination and …

Patient-derived monoclonal antibody neutralizes SARS-CoV-2 Omicron variants and confers full protection in monkeys

C Fenwick, P Turelli, D Ni, L Perez, K Lau… - Nature …, 2022 - nature.com
Abstract The SARS-CoV-2 Omicron variant has very high levels of transmission, is resistant
to neutralization by authorized therapeutic human monoclonal antibodies (mAb) and is less …

Reduced interferon antagonism but similar drug sensitivity in Omicron variant compared to Delta variant of SARS-CoV-2 isolates

D Bojkova, M Widera, S Ciesek, MN Wass, M Michaelis… - Cell research, 2022 - nature.com
Dear Editor, Omicron (B. 1.1. 529), is a heavily mutated and highly contagious SARS-CoV-2
variant, which is currently causing large outbreaks in many countries. Protection provided by …

Increased immune escape of the new SARS-CoV-2 variant of concern Omicron

J Hu, P Peng, X Cao, K Wu, J Chen, K Wang… - Cellular & Molecular …, 2022 - nature.com
On 24 November, a new detected variant B. 1.1. 529 of SARS-CoV-2 by South Africa was
reported to WHO. After only 2 days, this variant was designated as “variant of concern”(VOC) …

The omicron variant of SARS‐CoV‐2: understanding the known and living with unknowns

NE Ingraham, DH Ingbar - Clinical and translational medicine, 2021 - Wiley Online Library
The recently discovered Omicron variant of SARS‐CoV‐2 has rapidly burst into the public
and scientific eye, being detected in more than 26 countries around the world. Given its …