Mutations of mutS and mutL genes have been linked with the emergence of hypermutator
(HPM) phenotype in several bacteria. Nevertheless, there is scarce evidence that these …

The genus Acinetobacter encompasses a heterogeneous group of bacteria that are
ubiquitous in the natural environment due in part to their ability to adapt genetically to novel …

The Escherichia coli DNA Mismatch Repair (MMR) protein MutS exist as dimers and
tetramers in solution, and the identification of its functional oligomeric state has been matter …

We have recently described the presence of a high proportion of Pseudomonas aeruginosa
isolates (20%) with an increased mutation frequency (mutators) in the lungs of cystic fibrosis …

MutS, a component of the mismatch repair system begins the DNA reparation process by
recognizing base/base mismatches or small insertion/deletion loops. We have cloned the …

In prokaryotic mismatch repair the MutS protein and its homologs recognize the mismatches.
The mutS gene of naturally transformable Pseudomonas stutzeri ATCC 17587 (genomovar …

The mutator phenotype has been linked in several bacterial genera to a defect in the methyl-
mismatch repair system, in which the major components are MutS and MutL. This system is …

Interaction between MutS and the replication factor β clamp has been extensively studied in
a Mismatch Repair context; however, its functional consequences are not well understood …

Mutator strains spontaneously arise in bacterial populations under stress in an attempt to
increase evolutionary adaptation. Inactivation of the ubiquitous DNA mismatch repair …

MutS is part of the bacterial mismatch repair system that corrects point mutations and small
insertions/deletions that fail to be proof-read by DNA polymerase activity. In this work it is …