The mutB gene of Salmonella typhimurium is involved in a methylation-independent repair
pathway specific for A/G or A/C mismatches and is the homolog of the Escherichia coli mutY …

With a probe constructed from the wild-type gene, a DNA fragment containing the entire
mutT1 mutator gene was isolated and cloned into pUC18. Nucleotide sequence analysis …

The MutS, MutH and MutL proteins mediate methyl-directed-mismatch (MDM) repair in
Escherichia coli and Salmonella typhimurium. These proteins have been developed into …

The Escherichia coli dnaQ49 mutator allele maps at the dnaQ locus, the structural gene for
the epsilon subunit of the DNA polymerase III holoenzyme. Epsilon, when bound to the …

Background All life forms need both high genetic stability to survive as species and a degree
of mutability to evolve for adaptation, but little is known about how the organisms balance …

The mismatch repair (MMR) system is one of the key molecular devices that prokaryotic cells
have for ensuring fidelity of DNA replication. While the canonical MMR of E. coli involves 3 …

Antimutators are genetic mutants that produce mutations at reduced rates compared to the
wild type strain. They are interesting because they may provide insights into the …

Escherichia coli mutator mutD5 is the most potent mutator known. The mutD5 mutation
resides in the dnaQ gene encoding the proofreading exonuclease of DNA polymerase III …

Background Acinetobacter baylyi ADP1 is an ideal bacterial strain for high-throughput
genetic analysis as the bacterium is naturally transformable. Thus, ADP1 can be used to …

MutL assists the mismatch recognition protein MutS to initiate and coordinate mismatch
repair in species ranging from bacteria to humans. The MutL N‐terminal ATPase domain is …