Glioblastoma multiforme (GBM) is the most malignant primary adult brain tumor. The current
standard of care is surgical resection, radiation, and chemotherapy treatment, which extends …

Glioblastoma (GBM) is associated with a very dismal prognosis, and current therapeutic
options still retain an overall unsatisfactorily efficacy in clinical practice. Therefore, novel …

Psychotropic drugs can penetrate the blood–brain barrier and regulate the levels of
neurotransmitters and neuromodulators such as γ-aminobutyric acid, glutamate, serotonin …

Simple Summary Glioblastoma is a devastating malignancy that has continued to prove
resistant to a variety of therapeutics. No new systemic therapy has been approved for use …

Glioblastoma (GBM) is a malignant brain tumor with few therapeutic options. The disease
presents with a complex spectrum of genomic aberrations, but the pharmacological …

Glioblastoma (GBM) is one of the most common, deadly, and difficult-to-treat adult brain
tumors. Surgical removal of the tumor, followed by radiotherapy (RT) and temozolomide …

Glioblastoma is an aggressive form of brain cancer with well-established patterns of intra-
tumoral heterogeneity implicated in treatment resistance and progression. While regional …

Glioblastoma multiforme (GBM), the most common and aggressive primary brain tumor, has
a high mortality rate despite extensive efforts to develop new treatments. GBM exhibits both …

Abstract Background Glioblastoma Multiforme is the deadliest type of brain tumor and is
characterized by very poor prognosis with a limited overall survival. Current optimal …

Glioblastoma (GBM) is the most common primary malignant brain tumor in adults with an
extremely poor prognosis. There is a dire need to develop effective therapeutics to …