Burning eye syndrome: do neuropathic pain mechanisms underlie chronic dry eye?

JP Kalangara, A Galor, RC Levitt, ER Felix… - Pain …, 2016 - academic.oup.com
Objective. Dry eye is a multi-factorial disorder that manifests with painful ocular symptoms
and visual disturbances, which can only be partly attributed to tear dysfunction. This disorder …

Neuropathic pain and dry eye

A Galor, HR Moein, C Lee, A Rodriguez, ER Felix… - The ocular …, 2018 - Elsevier
Dry eye is a common, multifactorial disease currently diagnosed by a combination of
symptoms and signs. Its epidemiology and clinical presentation have many similarities with …

Evidence that dry eye represents a chronic overlapping pain condition

AE Levitt, A Galor, AR Chowdhury, ER Felix… - Molecular …, 2017 - journals.sagepub.com
Recent data suggest that corneal somatosensory dysfunction may be the underlying cause
of severe dry eye symptoms in the absence of ocular surface pathology seen in a subset of …

[HTML][HTML] Neuropathic ocular pain: an important yet underevaluated feature of dry eye

A Galor, RC Levitt, ER Felix, ER Martin… - Eye, 2015 - nature.com
Dry eye has gained recognition as a public health problem given its prevalence, morbidity,
and cost implications. Dry eye can have a variety of symptoms including blurred vision …

[HTML][HTML] New perspectives in the pathophysiology and treatment of pain in patients with dry eye disease

G Giannaccare, C Ghelardini, A Mancini… - Journal of Clinical …, 2021 - mdpi.com
Ocular discomfort and eye pain are frequently reported by patients with dry eye disease
(DED), and their management remains a real therapeutic challenge for the Ophthalmologist …

Neuropathic corneal pain and dry eye: a continuum of nociception

G Dieckmann, D Borsook, E Moulton - British Journal of …, 2022 - bjo.bmj.com
Throughout the body, damage to peripheral nerves normally involved in nociception may
produce a constellation of symptoms—including irritation, itchiness and pain. The …

Characteristics of ocular pain complaints in patients with idiopathic dry eye symptoms

JP Kalangara, A Galor, RC Levitt, DB Covington… - Eye & contact …, 2017 - journals.lww.com
Objective: The purpose of this study was to examine the severity and quality of ocular pain
complaints in patients with dry eye symptoms. Methods: Subjects with clinically relevant dry …

[PDF][PDF] Corneal nerve pathway function in individuals with dry eye symptoms

A Galor, ER Felix, W Feuer, RC Levitt… - Ophthalmology, 2021 - Elsevier
Dry eye (DE) disease is a multifactorial, chronic condition with a prevalence of 5-41 30%. 1
DE symptoms are a frequent presenting complaint to eye clinics and can include 42 …

[HTML][HTML] The potential role of neuropathic mechanisms in dry eye syndromes

CW Mcmonnies - Journal of optometry, 2017 - Elsevier
Dry eye syndromes can involve both nociceptive and neuropathic symptoms. Nociceptive
symptoms are the normal physiological responses to noxious stimuli. Neuropathic symptoms …

[HTML][HTML] Evidence that dry eye is a comorbid pain condition in a US veteran population

CJ Lee, RC Levitt, ER Felix, CD Sarantopoulos… - Pain …, 2017 - journals.lww.com
Objectives: To evaluate DE as a comorbid condition in the US veteran population. Methods:
Retrospective review of veterans seen in the Veterans Administration Healthcare System …