Molecular basis for chemical evolution of flavones to flavonols and anthocyanins in land plants
DD Li, R Ni, PP Wang, XS Zhang, PY Wang… - Plant …, 2020 - academic.oup.com
During the course of evolution of land plants, different classes of flavonoids, including
flavonols and anthocyanins, sequentially emerged, facilitating adaptation to the harsh …
flavonols and anthocyanins, sequentially emerged, facilitating adaptation to the harsh …
Evolution of Flavone Synthase I from Parsley Flavanone 3β-Hydroxylase by Site-Directed Mutagenesis
YH Gebhardt, S Witte, H Steuber, U Matern… - Plant …, 2007 - academic.oup.com
Abstract Flavanone 3 β-hydroxylase (FHT) and flavone synthase I (FNS I) are 2-oxoglutarate-
dependent dioxygenases with 80% sequence identity, which catalyze distinct reactions in …
dependent dioxygenases with 80% sequence identity, which catalyze distinct reactions in …
[HTML][HTML] Divergent evolution of flavonoid 2-oxoglutarate-dependent dioxygenases in parsley
S Martens, G Forkmann, L Britsch, F Wellmann… - FEBS letters, 2003 - Elsevier
Flavone synthases (FNSs) catalyze the oxidation of flavanones to flavones, ie the formation
of apigenin from (2S)-naringenin. While many plants express a microsomal-type FNS II, the …
of apigenin from (2S)-naringenin. While many plants express a microsomal-type FNS II, the …
Apiaceae FNS I originated from F3H through tandem gene duplication
Background Flavonoids are specialized metabolites with numerous biological functions in
stress response and reproduction of plants. Flavones are one subgroup that is produced by …
stress response and reproduction of plants. Flavones are one subgroup that is produced by …
Biochemical and genetic characterization of Arabidopsis flavanone 3β-hydroxylase
DK Owens, KC Crosby, J Runac, BA Howard… - Plant Physiology and …, 2008 - Elsevier
Flavanone 3β-hydroxylase (F3H; EC 1.14. 11.9) is a 2-oxoglutarate dependent dioxygenase
that catalyzes the synthesis of dihydrokaempferol, the common precursor for three major …
that catalyzes the synthesis of dihydrokaempferol, the common precursor for three major …
Metabolomic and genetic analyses of flavonol synthesis in Arabidopsis thaliana support the in vivo involvement of leucoanthocyanidin dioxygenase
R Stracke, RCH De Vos, L Bartelniewoehner… - Planta, 2009 - Springer
Abstract Flavonol synthase (FLS)(EC-number 1.14. 11.23), the enzyme that catalyses the
conversion of flavonols into dihydroflavonols, is part of the flavonoid biosynthesis pathway …
conversion of flavonols into dihydroflavonols, is part of the flavonoid biosynthesis pathway …
Characterization of two flavonol synthases with iron-independent flavanone 3-hydroxylase activity from Ornithogalum caudatum Jacq
YJ Sun, JM He, JQ Kong - BMC plant biology, 2019 - Springer
Background Flavonol synthase (FLS) is the key enzyme responsible for the biosynthesis of
flavonols, the most abundant flavonoids, which have diverse pharmaceutical effects …
flavonols, the most abundant flavonoids, which have diverse pharmaceutical effects …
The identification of maize and Arabidopsis type I flavone synthases links flavones with hormones and biotic interactions
ML Falcone Ferreyra, J Emiliani, EJ Rodriguez… - Plant …, 2015 - academic.oup.com
Flavones are a major group of flavonoids with diverse functions and are extensively
distributed in land plants. There are two different classes of FLAVONE SYNTHASE (FNS) …
distributed in land plants. There are two different classes of FLAVONE SYNTHASE (FNS) …
Molecular characterization and functional expression of flavonol 6-hydroxylase
D Anzellotti, RK Ibrahim - BMC Plant Biology, 2004 - Springer
Background Flavonoids, one of the major groups of secondary metabolites, play important
roles in the physiology, ecology and defence of plants. Their wide range of activities is the …
roles in the physiology, ecology and defence of plants. Their wide range of activities is the …
Characterization of the Brassica napus Flavonol Synthase Gene Family Reveals Bifunctional Flavonol Synthases
HM Schilbert, M Schöne, T Baier, M Busche… - Frontiers in plant …, 2021 - frontiersin.org
Flavonol synthase (FLS) is a key enzyme for the formation of flavonols, which are a subclass
of the flavonoids. FLS catalyzes the conversion of dihydroflavonols to flavonols. The enzyme …
of the flavonoids. FLS catalyzes the conversion of dihydroflavonols to flavonols. The enzyme …