Despite the many strides in the management of heart failure during the past 2 decades, the
efficacy of our current pharmacologic approach in heart failure is variable and is often …

Heart failure (HF) is one of the most prevalent cardiovascular diseases and is associated
with significant morbidity and a poor prognosis. Since the 1980s, HF phenotyping was …

Heart failure (HF), a heterogeneous syndrome of epidemic proportions, is increasingly
defined by its underlying molecular and genomic alterations. Molecular cardiac imaging has …

Objectives: Using molecular imaging techniques, we examined interstitial alterations during
postmyocardial infarction (MI) remodeling and assessed the efficacy of antiangiotensin and …

Abstract Purpose of Review Cardiovascular diseases are the leading cause of deaths
worldwide. Many complex cellular and molecular pathways lead to myocardial remodeling …

Cardiac left ventricular (LV) remodeling is the final common pathway of most primary
cardiovascular diseases that manifest clinically as heart failure (HF). The more advanced the …

As we pursue the high bar of optimal quality of care for patients with heart failure by targeting
appropriate patients with all indicated evidence-based, guideline-driven interventions, we …

Molecular imaging can detect and quantify pathophysiological processes underlying heart
failure, complementing evaluation of cardiac structure and function with other imaging …

As a young cardiology fellow in the 1980s, I cared for a man with severe heart failure. At that
time, it was believed that without angina, severe myocardial dysfunction from coronary artery …

Heart failure is a complex clinical syndrome arising from reduced cardiac contractile function
and affecting a significant portion of the adult population while increasing rapidly with age …