The importance of canonical versus noncanonical mechanisms for the generation of
angiotensins remains a major challenge that, in part, is heavily swayed by the relative …

Recent evidence suggests that angiotensin-(1-7) is a bioactive component of the renin-
angiotensin system that may oppose or, in certain situations contribute to the actions of Ang …

A total of 31 healthy volunteers [39±7 (SD) years] and 18 untreated essential hypertensive
subjects [43±9 years] collected urine for 24 h after a physical examination and laboratory …

In experimental animal models of hypertension, angiotensin (1–7)[ANG-(1–7)] is higher in
females compared with males; however, it is less clear whether the same applies to humans …

Evidence of endogenous angiotensin-(1–12)[Ang-(1–12)] may necessitate revision of the
accepted view that Ang I is the immediate peptide product derived from the precursor protein …

Abstract Angiotensin (Ang)-(1-7) is a bioactive component of the renin-angiotensin system
that is formed endogenously from either Ang I or Ang II. The first actions described for Ang-(1 …

Structure-activity studies of angiotensin II (Ang II) have clearly established that the carboxyl-
ter-minal phenylalanine is crucial for activation of angiotensin receptors associated with a …

During the last decade, knowledge of the actions of the various angiotensin peptides on the
cardiovascular system has dramatically increased. In addition to angiotensin II, the actions of …

The plasma concentrations of angiotensin (Ang) I, Ang II, and their metabolites (Ang (3-8),(4-
8),(5-8), and (3-4)) following in vitro ACE inhibitory activity were examined in young male …

Angiotensin-(1–12)[ANG-(1–12)], a new member of the renin-angiotensin system, is
recognized as a renin independent precursor for ANG II. However, the processing of ANG-(1 …