Both in clinical practice and in drug trials, combination treatment of hypertension plays a
fundamental role. This article reviews the features that make combined therapy with two …

The majority of patients with hypertension need at least two antihypertensive agents to
achieve blood pressure (BP) objectives. As current European guidelines for the treatment of …

Meticulous control of blood pressure is required in patients with hypertension to produce the
maximum reduction in clinical cardiovascular end points, especially in patients with …

Despite the availability of various classes of antihypertensive agents that lower blood
pressure by different primary actions, the treatment of hypertension remains a difficult task …

RATIONALE FOR DRUG COMBINATIONS: Essential hypertension is a heterogeneous
disease. Different factors might interact, in an individual patient, to increase blood pressure …

Aim: To review the various pharmacological approaches currently proposed for the
treatment of hypertension. Results: With the evolution of pharmacological treatment of …

Editor's Note: The American Society of Hypertension is publishing a series of Position
Papers in their official journals throughout the 2008–2011 years. The following Position …

Myocardial infarction, stroke, and congestive heart failure are the leading causes of death
and disability in developed countries. Hypertension is one of the most important risk factors …

Monotherapy is able to normalize blood pressure in less than a quarter of patients with
hypertension. However, for a disease of multifactorial pathogenesis like essential …

The goal of antihypertensive therapy is to abolish the risks associated with blood pressure
(BP) elevation without adversely affecting quality of life. Drug selection is based on efficacy …