Background: In patients with colorectal liver metastases, the possibility for radical liver
resection can be limited by oxaliplatin-induced sinusoidal obstruction syndrome (SOS). This …

Background: Sinusoidal obstruction syndrome (SOS) occurs in 50-70% of patients receiving
oxaliplatin for hepatic metastasis. Patients suffering from SOS preoperatively are at …

Background/Aim: Sinusoidal obstruction syndrome (SOS) after neoadjuvant chemotherapy
with oxaliplatin for colorectal liver metastases (CRLM) has been reported to lead to early …

Abstract Background and Aim Safe radical hepatectomy is important for patients with
colorectal liver metastases complicated by sinusoidal obstruction syndrome (SOS) after …

Aim Sinusoidal obstruction syndrome (SOS) induced by oxaliplatin‐including
chemotherapies (OXCx) is associated with impaired hepatic reserve and higher morbidity …

Aims Oxaliplatin is an important chemotherapeutic agent, used in the treatment of hepatic
colorectal metastases, and known to induce the sinusoidal obstruction syndrome (SOS) …

Purpose In recent years, multimodal treatment approaches have led to an increased median
survival time of patients with colorectal liver metastases. In particular, this results from new …

Vreuls CPH, Van Den Broek MA, Winstanley A, Koek GH, Wisse E, Dejong CH, Olde Damink
SWM, Bosman FT & Driessen A (2012) Histopathology 61, 314–318 Hepatic sinusoidal …

Objective: The aim of study was to investigate pharmacological treatment for sinusoidal
obstruction syndrome (SOS). Background: SOS is associated with oxaliplatin-based …

Aims The aim of this study was to investigate the relationship between the use of
bevacizumab (Bmab) in addition to oxaliplatin (OX), the development of sinusoidal …