Objective To validate and evaluate the performance metrics of the high‐throughput
semiconductor sequencing platform, Ion Proton®, in non‐invasive prenatal genetic …

< strong> Objectives</strong> To validate and evaluate an integrated protocol for non‐
invasive prenatal genetic screening (NIPS) for common fetal aneuploidies in a clinical …

Objectives To implement non‐invasive prenatal testing (NIPT) for fetal aneuploidies with
semiconductor sequencing in an academic cytogenomic laboratory and to evaluate the first …

Background Noninvasive prenatal testing (NIPT) to detect fetal aneuploidy using next-
generation sequencing on ion semiconductor platforms has become common. There are …

Objective Recent non-invasive prenatal testing (NIPT) technologies are based on next-
generation sequencing (NGS). NGS allows rapid and effective clinical diagnoses to be …

We compared clinical validity of two non-invasive prenatal screening (NIPS) methods for
fetal trisomies 13, 18, 21, and monosomy X. We recruited prospectively 2203 women at high …

Abstract Background Noninvasive prenatal tests (NIPTs) detect fetal chromosomal
anomalies with high clinical sensitivity and specificity. We examined the performance of a …

Objective As the first laboratory to offer massively parallel sequencing-based noninvasive
prenatal testing (NIPT) for fetal aneuploidies, Sequenom Laboratories has been able to …

Massively parallel sequencing (MPS) of cell-free fetal DNA from maternal plasma has
revolutionized our ability to perform noninvasive prenatal diagnosis. This approach avoids …

Noninvasive prenatal testing (NIPT) for fetal aneuploidies using cell-free fetal DNA in
maternal plasma has revolutionized the field of prenatal care and methods using massively …