Macrophage plasticity, polarization and function in response to curcumin, a diet-derived polyphenol, as an immunomodulatory agent
Monocytes and macrophages are important cells of the innate immune system that have
diverse functions, including defense against invading pathogens, removal of dead cells by …
diverse functions, including defense against invading pathogens, removal of dead cells by …
[HTML][HTML] Curcumin modulates macrophage polarization through the inhibition of the toll-like receptor 4 expression and its signaling pathways
Y Zhou, T Zhang, X Wang, X Wei, Y Chen… - Cellular Physiology and …, 2015 - karger.com
Background: Curcumin, the active ingredient in curcuma rhizomes, has a wide range of
therapeutic effects. However, its atheroprotective activity in human acute monocytic …
therapeutic effects. However, its atheroprotective activity in human acute monocytic …
Curcumin inhibits immunostimulatory function of dendritic cells: MAPKs and translocation of NF-κB as potential targets
GY Kim, KH Kim, SH Lee, MS Yoon, HJ Lee… - The Journal of …, 2005 - journals.aai.org
Curcumin has been shown to exhibit anti-inflammatory, antimutagenic, and anticarcinogenic
activities. However, the effect of curcumin on the maturation and immunostimulatory function …
activities. However, the effect of curcumin on the maturation and immunostimulatory function …
Therapeutic effects of curcumin in inflammatory and immune‐mediated diseases: A nature‐made jack‐of‐all‐trades?
Curcumin is a dietary polyphenol from turmeric with numerous pharmacological activities.
Novel animal and human studies indicate that curcumin can affect different immune cells …
Novel animal and human studies indicate that curcumin can affect different immune cells …
Reprogramming M1-to-M2 Phenotype to Alleviate Inflammation: Using Liposomal Curcumin as a Tool to Redefine Macrophage Functionality
The versatile nature of macrophages and their ability to switch between various activation
states plays a pivotal role in both promoting and inhibiting inflammatory processes. In …
states plays a pivotal role in both promoting and inhibiting inflammatory processes. In …
Curcumin and chemokines: mechanism of action and therapeutic potential in inflammatory diseases
Chemokines belong to the family of cytokines with chemoattractant properties that regulate
chemotaxis and leukocyte migration, as well as the induction of angiogenesis and …
chemotaxis and leukocyte migration, as well as the induction of angiogenesis and …
Immunomodulatory and therapeutic activity of curcumin
Inflammation is a disease of vigorous uncontrolled activated immune responses.
Overwhelming reports have suggested that the modulation of immune responses by …
Overwhelming reports have suggested that the modulation of immune responses by …
Curcumin: a modulator of inflammatory signaling pathways in the immune system
KR Kahkhaie, A Mirhosseini, A Aliabadi… - …, 2019 - Springer
Curcumin is a natural compound derived from the spice, turmeric, that has been extensively
reported for its efficacy in controlling or treatment of several inflammatory diseases. There is …
reported for its efficacy in controlling or treatment of several inflammatory diseases. There is …
Modulation of neutrophil motility by curcumin: implications for inflammatory bowel disease
CB Larmonier, MT Midura-Kiela… - Inflammatory bowel …, 2011 - academic.oup.com
Background Neutrophils (PMN) are the first cells recruited at the site of inflammation. They
play a key role in the innate immune response by recognizing, ingesting, and eliminating …
play a key role in the innate immune response by recognizing, ingesting, and eliminating …
Chlorogenic acid potentiates the anti-inflammatory activity of curcumin in LPS-stimulated THP-1 cells
The anti-inflammatory effects of curcumin are well documented. However, the bioavailability
of curcumin is a major barrier to its biological efficacy. Low-dose combination of …
of curcumin is a major barrier to its biological efficacy. Low-dose combination of …