Background Low lung function, measured using spirometry, has been associated with
mortality from cardiovascular disease, but whether this is explained by airflow obstruction or …

Background Chronic obstructive pulmonary disease (COPD) is associated with
hemodynamic changes in the pulmonary vasculature. However, cardiac effects are not fully …

Cor pulmonale has long been described in very severe chronic obstructive pulmonary
disease (COPD) and emphysema. Cross-sectional results from population-based studies …

Background: Pulmonary dysfunction predicts incident cardiovascular disease (CVD).
Objectives: The purpose of this study was to evaluate whether longitudinal decline in lung …

Accurately estimating left atrial (LA) volume with Doppler echocardiography remains
challenging. Using angiography for validation, Marino et al.(Marino P, Prioli AM, Destro G …

Background Lung function is constantly changing over the life course. Although the relation
of cross-sectional lung function measure and adverse outcomes has been reported, data on …

To develop more sensitive measures of impaired cardiac function in patients with pulmonary
hypertension (PH), since detection of impaired right ventricular (RV) function is important in …

Background Hyperinflation refers to a nonspecific increase in absolute lung volumes and
has a poor prognosis in COPD. The relative contribution of increased airways resistance …

Rationale: The aim of the ALICE (Airflow Limitation in Cardiac Diseases in Europe) study
was to investigate the prevalence of airflow limitation in patients with ischemic heart disease …

Background Right ventricular function is a key determinant of exercise capacity and survival
in pulmonary arterial hypertension (PAH). We aimed to study the predictors of right …