[HTML][HTML] Multiple biological effects of an iridoid glucoside, catalpol, and its underlying molecular mechanisms
SK Bhattamisra, KH Yap, V Rao, H Choudhury - Biomolecules, 2019 - mdpi.com
Catalpol, an iridoid glucoside, is widely distributed in many plant families and is primarily
obtained from the root of Rehmannia glutinosa Libosch. Rehmannia glutinosa is a plant very …
obtained from the root of Rehmannia glutinosa Libosch. Rehmannia glutinosa is a plant very …
[HTML][HTML] Molecular and biochemical pathways of catalpol in alleviating diabetes mellitus and its complications
SK Bhattamisra, HM Koh, SY Lim, H Choudhury… - Biomolecules, 2021 - mdpi.com
Catalpol isolated from Rehmannia glutinosa is a potent antioxidant and investigated against
many disorders. This review appraises the key molecular pathways of catalpol against …
many disorders. This review appraises the key molecular pathways of catalpol against …
Catalpol exerts antidepressant-like effects by enhancing anti-oxidation and neurotrophy and inhibiting neuroinflammation via activation of HO-1
X Wu, C Liu, J Wang, Y Guan, L Song, R Chen… - Neurochemical …, 2022 - Springer
Catalpol is an iridoid glycoside with rich content, rich nutrition, and numerous biological
activities in Rehmanniae Radix contained in classic antidepressant prescriptions in Chinese …
activities in Rehmanniae Radix contained in classic antidepressant prescriptions in Chinese …
Effects of catalpol on Alzheimer's disease and its mechanisms
H Chen, C Deng, Z Meng… - … Based Complementary and …, 2022 - Wiley Online Library
Alzheimer's disease (AD) is a degenerative disease of the central nervous system
characterized by memory loss and cognitive dysfunction. With the increasing aging of the …
characterized by memory loss and cognitive dysfunction. With the increasing aging of the …
[HTML][HTML] Antidiabetic and antioxidant effects of catalpol extracted from Rehmannia glutinosa (Di Huang) on rat diabetes induced by streptozotocin and high-fat, high …
H Zhu, Y Wang, Z Liu, J Wang, D Wan, S Feng… - Chinese medicine, 2016 - Springer
Background Diabetes, associated with hyperlipidemia and oxidative stress, would lead to an
increased production of reactive oxygen species. Rehmannia glutinosa (Di Huang) is widely …
increased production of reactive oxygen species. Rehmannia glutinosa (Di Huang) is widely …
Antidepressant mechanism of catalpol: Involvement of the PI3K/Akt/Nrf2/HO-1 signaling pathway in rat hippocampus
J Wang, R Chen, C Liu, X Wu, Y Zhang - European journal of pharmacology, 2021 - Elsevier
Catalpol is a major compound in Rehmanniae Radix with outstanding medicinal and
nutritional values. Our previous studies have demonstrated catalpol's antidepressant effect …
nutritional values. Our previous studies have demonstrated catalpol's antidepressant effect …
Further pharmacological evidence of the neuroprotective effect of catalpol from Rehmannia glutinosa
X Zhang, A Zhang, B Jiang, Y Bao, J Wang, L An - Phytomedicine, 2008 - Elsevier
We have previously evaluated the neuroprotective effect of catalpol on aging mice induced
by d-galactose, in which catalpol treatment ameliorated cognition deficits and attenuated …
by d-galactose, in which catalpol treatment ameliorated cognition deficits and attenuated …
Therapeutic potential of catalpol and geniposide in Alzheimer's and Parkinson's diseases: a snapshot of their underlying mechanisms
X Zhang, K Liu, M Shi, L Xie, M Deng, H Chen… - Brain Research Bulletin, 2021 - Elsevier
Rehmannia glutinosa, the fresh or dried root of Rehmannia glutinosa (Gaertn.) Libosch. ex
Fisch. & Mey., and Gardenia, the fruit of Gardenia jasminoides Ellis from Rubiaceae, both …
Fisch. & Mey., and Gardenia, the fruit of Gardenia jasminoides Ellis from Rubiaceae, both …
Catalpol: a potential therapeutic for neurodegenerative diseases
B Jiang, RF Shen, J Bi, XS Tian… - Current Medicinal …, 2015 - ingentaconnect.com
Neurodegenerative disorders, eg, Alzheimer's disease (AD) and Parkinson's disease (PD)
are characterized by the progressive loss of neurons and subsequent cognitive decline …
are characterized by the progressive loss of neurons and subsequent cognitive decline …
[HTML][HTML] Catalpol preserves neural function and attenuates the pathology of Alzheimer's disease in mice
JZ Huang, J Wu, S Xiang, S Sheng… - Molecular …, 2016 - spandidos-publications.com
Alzheimer's disease (AD) is the most common form of dementia and there currently are no
effective treatment strategies available. Catalpol is an iridoid glucoside, and large quantities …
effective treatment strategies available. Catalpol is an iridoid glucoside, and large quantities …