[HTML][HTML] Oxytocin may have a therapeutical potential against cardiovascular disease. Possible pharmaceutical and behavioral approaches

B Buemann, K Uvnäs-Moberg - Medical hypotheses, 2020 - Elsevier
Based on the ancient role of oxytocin and its homologues as amplifiers of reproduction we
argue for an evolutionary coupling of oxytocin to signaling pathway which support …

Oxytocin: potential to mitigate cardiovascular risk

AB Reiss, DS Glass, E Lam, AD Glass, J De Leon… - Peptides, 2019 - Elsevier
Cardiovascular disease (CVD) remains the leading cause of death worldwide, despite
multiple treatment options. In addition to elevated lipid levels, oxidative stress and …

Oxytocin: old hormone, new drug

J Gutkowska, M Jankowski - Pharmaceuticals, 2009 - mdpi.com
Oxytocin (OT), traditionally associated with reproductive functions, was revisited recently,
and several new functions in cardiovascular regulation were discovered. These functions …

Oxytocin revisited: its role in cardiovascular regulation

J Gutkowska, M Jankowski - Journal of neuroendocrinology, 2012 - Wiley Online Library
Traditionally associated with female reproduction, oxytocin (OT) was revisited recently and
was revealed to have several new roles in the cardiovascular system. Functional OT …

[HTML][HTML] Oxytocin is a principal hormone that exerts part of its effects by active fragments

KU Moberg, L Handlin, K Kendall-Tackett… - Medical hypotheses, 2019 - Elsevier
Oxytocin is a nonapeptide consisting of a cyclic six amino-acid structure and a tail of three
amino acids. It was originally known for its ability to induce milk ejection and to stimulate …

The long way of oxytocin from the uterus to the heart in 70 years from its discovery

C Camerino - International Journal of Molecular Sciences, 2023 - mdpi.com
The research program on oxytocin started in 1895, when Oliver and Schafer reported that a
substance extracted from the pituitary gland elevates blood pressure when injected …

Cardiovascular effects of oxytocin

M Petersson - Progress in brain research, 2002 - Elsevier
The well known effects of oxytocin on uterine contraction and milk ejection were found as
early as the beginning of the 20th century. Since then many other effects of oxytocin have …

Central nervous system actions of oxytocin and modulation of behavior in humans

MM McCarthy, M Altemus - Molecular medicine today, 1997 - cell.com
The posterior pituitary hormone oxytocin has modulatory effects on neural functioning that
are significant to the regulation of behavior. Basic research in animals has established the …

Oxytocin, a mediator of anti-stress, well-being, social interaction, growth and healing

K Uvnas-Moberg, M Petersson - Zeitschrift fur Psychosomatische …, 2005 - europepmc.org
The neuroendocrine and physiological systems related to pain and stress have long been
subjected to study. More recently, the corresponding systems promoting anti-stress and …

Is oxytocin “nature's medicine”?

CS Carter, WM Kenkel, EL MacLean, SR Wilson… - Pharmacological …, 2020 - ASPET
Oxytocin is a pleiotropic, peptide hormone with broad implications for general health,
adaptation, development, reproduction, and social behavior. Endogenous oxytocin and …