Purpose Several in vitro systems have been reported to model human implantation;
however, the molecular dynamics of the trophoblast vs. the epithelial substrate during …

Research question Which are the early compartment-specific transcriptional responses of
the trophoblast and the endometrial epithelium throughout early attachment during …

Objective To establish a model of human implantation that responds to hormonal stimuli and
can differentiate between endometrium from fertile women and those with idiopathic …

Adhesive interactions of trophoblast cells with the endometrium are essential for embryo
implantation in the uterus. Choriocarcinoma cells, the malignant counterpart of trophoblast …

STUDY QUESTION How do interactions between blastocyst-stage embryos and endometrial
epithelial cells regulate the early stages of implantation in an in vitro model? SUMMARY …

A novel in vitro model was developed to study attachment and invasion of choriocarcinoma
cell spheroids using pre-cultured secretory phase human endometrium as a host tissue …

STUDY QUESTION What are the changes in human embryos, in terms of morphology and
gene expression, upon attachment to endometrial epithelial cells? SUMMARY ANSWER …

STUDY QUESTION Do maternal endometrial epithelial cell (EEC) differentiation and polarity
impact the invasive capacity of extravillous trophoblast (EVT) cells during early human …

Interest in mechanisms of embryo implantation is increasing, particularly with the realization
that failure of implantation after in vitro fertilization and embryo transfer places significant …

During implantation, a symphony of interaction between the trophoblast originated from the
trophectoderm of the implanting blastocyst and the endometrium leads to a successful …