DISCUSSION Dr. Tator: Could you comment on ways to get pharmacokinetics data for a
given drug? You mentioned HPLC for plasma and tissue drug levels. What about …

Pharmacological treatment of acute spinal cord injury: current status and future prospects Page 1
Paraplegia 30 (1992) 102-107 © 1992 International Medical Society of Paraplegia …

The North American Clinical Trials Network (NACTN) for the Treatment of Spinal Cord Injury
is a consortium of 10 neurosurgery departments, a data management center, and a …

Introduction: Secondary spinal cord injury (SCI) sets on immediately after trauma and,
despite prompt treatment, may become chronic. SCI is a complex condition and presents …

Spinal cord injury often results in devastating physical, psychological, and economic
disabilities. Research efforts are directed toward providing prognostic outcome data and …

Abstract USING DATA FROM the Second National Acute Spinal Cord Injury Study (NASCIS
II), the authors sought to characterize the role of surgery in the management of traumatic …

The major impetus of basic spinal cord injury (SCI) research is that therapeutic interventions
can be devised to prevent or reduce disability. For years, there was doubt about the prospect …

Therecently published results of the National Acute Spinal Cord Injury Study (NASCIS II)
have complicated studies of acute spinal cord injury treatments in several ways. First …

Study design: Experimental laboratory investigations in paraplegic rats. Objective: In order to
understand why acute spinal cord injury (SCI) changes the disposition of some, but not all …

DISCUSSION Dr. Hsu: I would like to reiterate the importance of controlling the biologic
variables. Drs. Stokes and Young have shown us very impressive results showing that …