In the mammalian brain, glutamate is regarded to be the primary excitatory neurotransmitter
due to its widespread distribution and wide range of metabolic functions. Glutamate plays …

Glutamate is an excitatory neurotransmitter, but may also act as an endogenous neurotoxin.
There is good evidence for an involvement of the glutamatergic system in the …

Alzheimer's disease (AD) is an age-related dementia and neurodegenerative disorder,
characterized by Aβ and tau protein deposition impairing learning, memory and suppressing …

Glutamate is the most important excitatory neurotransmitter in the central nervous system. In
the process, glutamate fulfills numerous physiological functions, but also plays an important …

This introductory article to the special edition on glutamate neurotransmission in
neuropsychiatric disorders provides an overview of glutamate neurotransmitter system …

Glutamate is the primary excitatory neurotransmitter of the brain. Cellular homeostasis of
glutamate is of paramount importance for normal brain function and relies on an intricate …

Alzheimer's disease affects nearly 5 million Americans currently and, as a result of the baby
boomer cohort, is predicted to affect 14 million Americans and 22 million persons totally …

Aging is a naturally occurring decline of physiological processes and biological pathways
that affects both the structural and functional integrity of the body and brain. These …

Glutamate is the primary excitatory neurotransmitter in neurons and glia. N-methyl-d-
aspartate (NMDA), α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), and …

L-Glutamic acid (Glu) is accepted as the major excitatory neurotransmitter in the nervous
system, although other acidic amino acids such as L-aspartic acid and L-homocysteic acid …