The linkage between microRNA and cancer and its delivery as cancer therapy: A mini-review

SUFS Najmuddin, AA Kamarudin, SA Sani… - Cellular and Molecular …, 2023 - cellmolbiol.org
The central dogma of molecular biology was no longer" central" after ground-breaking
discoveries conveyed gene expression involves more complex physiological functions in …

Exploiting the therapeutic potential of microRNAs in human cancer

WCS Cho - Expert opinion on therapeutic targets, 2012 - Taylor & Francis
Dysregulation of microRNAs (miRNAs) has been widely shown to be associated with the
development and progression of cancer. Recent studies discovered a handful of miRNAs …

[HTML][HTML] MicroRNA therapeutics in cancer: current advances and challenges

S Reda El Sayed, J Cristante, L Guyon, J Denis… - Cancers, 2021 - mdpi.com
Simple Summary Cancer is a complex disease associated with deregulation of numerous
genes. In addition, redundant cellular pathways limit efficiency of monotarget drugs in …

Therapeutic microRNA delivery strategies with special emphasis on cancer therapy and tumorigenesis: current trends and future challenges

C Chakraborty, ZH Wen… - Current drug …, 2016 - ingentaconnect.com
Background: Over the decade, miRNAs are the most important molecules for the
biopharmaceutical industry due to their relation with several human diseases. Presently, the …

[HTML][HTML] miRacle of microRNA-driven cancer nanotherapeutics

G Kara, B Arun, GA Calin, B Ozpolat - Cancers, 2022 - mdpi.com
Simple Summary The discovery of microRNAs has revolutionized the world of science and
opened up new opportunities in cancer treatment. miRNA dysregulation plays a crucial role …

[HTML][HTML] miRNAs as targets for cancer treatment: Therapeutics design and delivery

F Li, RI Mahato - Preface. Adv. Drug Deliv. Rev, 2015 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are a class of post-transcriptional gene expression modulators. In the
past two decades, over 1500 human miRNAs were discovered. Each miRNA controls …

[HTML][HTML] Modulating microRNAs in cancer: Next-generation therapies

N Arghiani, K Shah - Cancer Biology & Medicine, 2022 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are a class of endogenously expressed non-coding regulators of the
genome with an ability to mediate a variety of biological and pathological processes. There …

[HTML][HTML] microRNAs as novel therapeutics in cancer

G Romano, M Acunzo, P Nana-Sinkam - Cancers, 2021 - mdpi.com
Simple Summary Over the last few years, we have witnessed incredible advancements in
anti-tumor drug development. microRNAs, a class of small non-coding RNAs dysregulated …

[HTML][HTML] MicroRNA as a potential therapeutic molecule in cancer

J Szczepanek, M Skorupa, A Tretyn - Cells, 2022 - mdpi.com
Small noncoding RNAs, as post-translational regulators of many target genes, are not only
markers of neoplastic disease initiation and progression, but also markers of response to …

MiRNAs in human cancers: the diagnostic and therapeutic implications

Q Wu, Z Yang, Y Shi, D Fan - Current Pharmaceutical Design, 2014 - ingentaconnect.com
From chemotherapy and radiotherapy to molecular targeted therapy, in recent decades, we
have witnessed the acceleration of cancer treatments. However, nowadays, it has …