A genome-wide linkage and association scan reveals novel loci for hypertension and blood pressure traits
Hypertension is caused by the interaction of environmental and genetic factors. The
condition which is very common, with about 18% of the adult Hong Kong Chinese …
condition which is very common, with about 18% of the adult Hong Kong Chinese …
Genome-wide association studies: contribution of genomics to understanding blood pressure and essential hypertension
GB Ehret - Current hypertension reports, 2010 - Springer
Contemporary genomic tools now allow the fast and reliable genotyping of hundreds of
thousands of variants and permit an unbiased interrogation of the common variability across …
thousands of variants and permit an unbiased interrogation of the common variability across …
Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension
Hypertension is a common disorder and the leading risk factor for cardiovascular disease
and premature deaths worldwide. Genome-wide association studies (GWASs) in the …
and premature deaths worldwide. Genome-wide association studies (GWASs) in the …
Genome‐Wide Association Studies of Hypertension: Light at the End of the Tunnel
CE Hastie, S Padmanabhan… - International journal of …, 2010 - Wiley Online Library
Despite its significant genetic component, the study of hypertension by genome‐wide
association presents more challenges than other common complex diseases. Its high …
association presents more challenges than other common complex diseases. Its high …
Genomewide linkage scan of resting blood pressure: HERITAGE Family Study
T Rice, T Rankinen, YC Chagnon, MA Province… - …, 2002 - Am Heart Assoc
The purpose of this study was to search for genomic regions influencing resting systolic
(SBP) and diastolic (DBP) blood pressure (BP) in sedentary families (baseline), and for …
(SBP) and diastolic (DBP) blood pressure (BP) in sedentary families (baseline), and for …
[HTML][HTML] Eight blood pressure loci identified by genome-wide association study of 34,433 people of European ancestry
Elevated blood pressure is a common, heritable cause of cardiovascular disease worldwide.
To date, identification of common genetic variants influencing blood pressure has proven …
To date, identification of common genetic variants influencing blood pressure has proven …
Genome-wide association study identifies eight loci associated with blood pressure
Elevated blood pressure is a common, heritable cause of cardiovascular disease worldwide.
To date, identification of common genetic variants influencing blood pressure has proven …
To date, identification of common genetic variants influencing blood pressure has proven …
Hypertension susceptibility genes on chromosome 2p24-p25 in a general Japanese population
K Kamide, Y Kokubo, J Yang, C Tanaka… - Journal of …, 2005 - journals.lww.com
Background Genome-wide scans from Italy and China suggest a hypertension-susceptible
locus between D2S2278 (nucleotides 11 245 080–11 245 358) and D2S168 (nucleotides …
locus between D2S2278 (nucleotides 11 245 080–11 245 358) and D2S168 (nucleotides …
The genetic architecture of blood pressure variation
High blood pressure affects over 1 billion people worldwide and is responsible for 50% of all
cardio vascular deaths. Despite numerous candidate gene and linkage studies, no …
cardio vascular deaths. Despite numerous candidate gene and linkage studies, no …
Genome-wide scan for blood pressure suggests linkage to chromosome 11, and replication of loci on 16, 17, and 22
M de Lange, TD Spector, T Andrew - Hypertension, 2004 - Am Heart Assoc
Hypertension was one of the first complex traits to be studied and is thought to be influenced
by polygenic and multiple environmental risk factors. Several genomic studies have found …
by polygenic and multiple environmental risk factors. Several genomic studies have found …