[HTML][HTML] Non-alcoholic fatty liver disease induces signs of Alzheimer's disease (AD) in wild-type mice and accelerates pathological signs of AD in an AD model
DG Kim, A Krenz, LE Toussaint, KJ Maurer… - Journal of …, 2016 - Springer
Background Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease afflicting
about one third of the world's population and 30% of the US population. It is induced by …
about one third of the world's population and 30% of the US population. It is induced by …
[HTML][HTML] Non-alcoholic fatty liver disease, and the underlying altered fatty acid metabolism, reveals brain hypoperfusion and contributes to the cognitive decline in APP …
A Pinçon, O De Montgolfier, N Akkoyunlu, C Daneault… - Metabolites, 2019 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD), the leading cause of chronic liver disease, is
associated with cognitive decline in middle-aged adults, but the mechanisms underlying this …
associated with cognitive decline in middle-aged adults, but the mechanisms underlying this …
[HTML][HTML] Novel insights into non-alcoholic fatty liver disease and dementia: insulin resistance, hyperammonemia, gut dysbiosis, vascular impairment, and inflammation
SY Cheon, J Song - Cell & Bioscience, 2022 - Springer
Non-alcoholic fatty liver disease (NAFLD) is a metabolic disease characterized by multiple
pathologies. The progression of dementia with NAFLD may be affected by various risk …
pathologies. The progression of dementia with NAFLD may be affected by various risk …
[HTML][HTML] Chronic inflammation aggravates metabolic disorders of hepatic fatty acids in high-fat diet-induced obese mice
L Zhao, S Zhong, H Qu, Y Xie, Z Cao, Q Li, P Yang… - Scientific reports, 2015 - nature.com
The prevalence of nonalcoholic fatty liver disease (NAFLD) increases with increasing body
mass index (BMI). However, approximately 40–50% of obese adults do not develop hepatic …
mass index (BMI). However, approximately 40–50% of obese adults do not develop hepatic …
[HTML][HTML] The effect of dietary fat consumption on Alzheimer's disease pathogenesis in mouse models
A Amelianchik, L Sweetland-Martin… - Translational Psychiatry, 2022 - nature.com
Alzheimer's disease (AD) is a fatal cognitive disorder with proteinaceous brain deposits,
neuroinflammation, cerebrovascular dysfunction, and extensive neuronal loss over time. AD …
neuroinflammation, cerebrovascular dysfunction, and extensive neuronal loss over time. AD …
Association between non‐alcoholic fatty liver disease and the risk of dementia: a nationwide cohort study
Abstract Background and Aims Little is known about the association between non‐alcoholic
fatty liver disease (NAFLD) and dementia. Given that hepatic steatosis is linked to abnormal …
fatty liver disease (NAFLD) and dementia. Given that hepatic steatosis is linked to abnormal …
[HTML][HTML] High-fat diet exacerbates cognitive decline in mouse models of Alzheimer's disease and mixed dementia in a sex-dependent manner
OJ Gannon, LS Robison, AE Salinero… - Journal of …, 2022 - Springer
Abstract Background Approximately 70% of Alzheimer's disease (AD) patients have co-
morbid vascular contributions to cognitive impairment and dementia (VCID); this highly …
morbid vascular contributions to cognitive impairment and dementia (VCID); this highly …
Short-term high-fat diet modulates several inflammatory, ER stress, and apoptosis markers in the hippocampus of young mice
SCBR Nakandakari, VR Munoz, GK Kuga… - Brain, Behavior, and …, 2019 - Elsevier
The consumption of saturated fatty acids is one of the leading risk factors for Alzheimer's
Disease (AD) development. Indeed, the short-term consumption of a high-fat diet (HFD) is …
Disease (AD) development. Indeed, the short-term consumption of a high-fat diet (HFD) is …
[HTML][HTML] Western diet induces impairment of liver-brain Axis Accelerating neuroinflammation and amyloid pathology in Alzheimer's disease
A Wiȩckowska-Gacek… - Frontiers in aging …, 2021 - frontiersin.org
Alzheimer's disease (AD) is an aging-dependent, irreversible neurodegenerative disorder
and the most common cause of dementia. The prevailing AD hypothesis points to the central …
and the most common cause of dementia. The prevailing AD hypothesis points to the central …
[HTML][HTML] Risk of dementia or cognitive impairment in non-alcoholic fatty liver disease: a systematic review and meta-analysis
L Wang, B Sang, Z Zheng - Frontiers in aging neuroscience, 2022 - frontiersin.org
Objectives To investigate whether non-alcoholic fatty liver disease (NAFLD) increases the
risk of dementia or cognitive impairment. Methods A systematic search of the literature in the …
risk of dementia or cognitive impairment. Methods A systematic search of the literature in the …