Background Histidine-tryptophan-ketoglutarate (HTK) and del Nido (DN) cardioplegia are
intracellular-type and extracellular-type solution respectively, both can provide a long period …

Objective del Nido solution (DNS) is a single-dose cardioplegia designed for pediatric use
proposed to offer superior myocardial protection in adults. However, few data support this …

OBJECTIVES In recent years, the use of del Nido (DN) cardioplegia has been reported in
single-valve surgery or isolated coronary artery bypass surgery with acceptable outcomes …

Abstract Objective While del Nido (DN) cardioplegia is increasingly used in cardiac surgery,
knowledge is limited in its safety profile for operations with prolonged crossclamp time …

Background: Del Nido (DN) cardioplegia is increasingly popular in adult cardiac surgery. It
allegedly allows for up to 90 minutes of safe myocardial ischemia with a single dose. Aims …

Objective The use of del Nido cardioplegia (DNC) was initially adopted in the field of
pediatric cardiac surgery. Several studies in adult patients suggested there were no …

Objective Equivalent myocardial protection and clinical outcomes have been shown with the
use of del Nido cardioplegia (DC) compared with blood cardioplegia (BC) in adult isolated …

Abstract Background and Aims The immediate postischemic period is marked by elevated
intracellular calcium levels, which can lead to irreversible myocyte injury. Del Nido …

Objective Del Nido cardioplegia (DC) has been used extensively in pediatric cardiac surgery
but the efficacy and safety in adults remains uncertain. Our objective was to perform a …

Cardioplegia is an important strategy for myocardial protection during cardiac surgery. This
meta-analysis was to compare the effects of del Nido and conventional cardioplegia in adult …