[HTML][HTML] Efficacy and safety of Afalaza in men with symptomatic benign prostatic hyperplasia at risk of progression: a multicenter, double-blind, placebo-controlled …

D Pushkar, A Vinarov, L Spivak… - … European Journal of …, 2018 - ncbi.nlm.nih.gov
Results IPSS mean change was-3.7±3.0 (95% CI-4.3 to-3.2) after 12 months of Afalaza (vs.-
2.9±2.4; 95% CI-3.3 to-2.4 in placebo; р= 0.02). Qmax growth was 2.5±4.3 ml/s (vs. 1.4±3.3 …

The natural history of benign prostatic hyperplasia

JM Fitzpatrick - BJU international, 2006 - Wiley Online Library
The progression of benign prostatic hyperplasia (BPH) can be defined as a deterioration of
clinical variables such as lower urinary tract symptoms (LUTS), health‐related quality of life …

A review of combination therapy in patients with benign prostatic hyperplasia

KT McVary - Clinical therapeutics, 2007 - Elsevier
BACKGROUND:: Trials of monotherapy with α1-adrenergic-receptor antagonists (α1ARAs)
and 5a-reductase inhibitors (5ARIs) have found that the former drug class is effective in …

Alfuzosin 10 mg once daily for treating benign prostatic hyperplasia: a 3‐year experience in real‐life practice

G Vallancien, M Emberton, A Alcaraz… - BJU …, 2008 - Wiley Online Library
OBJECTIVES To assess the 3‐year efficacy and safety of the selective α1‐blocker alfuzosin
at 10 mg once daily in men with lower urinary tract symptoms (LUTS) suggestive of benign …

Sustained-release alfuzosin, finasteride and the combination of both in the treatment of benign prostatic hyperplasia

FMJ Debruyne, A Jardin, D Colloi, L Resel… - European …, 1998 - karger.com
Objectives: To assess the additive benefit of combining an α 1-blocker and a 5α-reductase
inhibitor. Methods: This European, randomized, double-blind, multicenter trial involved …

Long-term results of medical treatment in benign prostatic hyperplasia

CI Kim, HS Chang, BK Kim, CH Park - Urology, 2006 - Elsevier
OBJECTIVES: In real-life clinical practice, we determined the incidence of acute urinary
retention (AUR) and benign prostatic hyperplasia (BPH)-related surgery in patients with BPH …

State of the art on the efficacy and tolerability of alpha1-adrenoceptor antagonists in patients with lower urinary tract symptoms suggestive of benign prostatic …

B Djavan, C Chapple, S Milani, M Marberger - Urology, 2004 - goldjournal.net
In 1999, a meta-analysis on the efficacy and tol-erability of α1-adrenoceptor (α1-AR)
antagonists in treating lower urinary tract symptoms (LUTS) suggestive of benign prostatic …

Evaluation of patient outcome after discontinuation of alfuzosin treatment for benign prostatic hyperplasia: a multicentre, prospective study

JH Chung, JY Lee, DH Kang, JK Jo… - … Journal of Clinical …, 2013 - Wiley Online Library
Aims: The aim of this study was to assess patient outcome after discontinuation of alfuzosin
treatment in patients with benign prostatic hyperplasia (BPH). Methods: This study included …

[HTML][HTML] α-Blocker monotherapy and α-blocker plus 5-Alpha-reductase inhibitor combination treatment in benign prostatic hyperplasia; 10 years' long-term results

TJ Shin, CI Kim, CH Park, BH Kim… - Korean journal of …, 2012 - ncbi.nlm.nih.gov
Purpose We compared the effects of alpha-adrenergic receptor blocker (α-blocker)
monotherapy with those of combination therapy with α-blocker and 5-alpha-reductase …

Combination therapy for the pharmacological management of benign prostatic hyperplasia: rationale and treatment options

JS Sandhu, ED Vaughan - Drugs & aging, 2005 - Springer
The management of symptomatic benign prostatic hyperplasia (BPH) continues to evolve,
with new techniques and forms of medical management being introduced and traditional …