[图书][B] Excavating the Genome Mine of Pseudomonas putida KT2440

MR Incha - 2023 - search.proquest.com
Pseudomonas putida is an important chassis strain for the valorization of lignin. While we
know much about this host and have developed numerous tools to engineer it, we still lack a …

Fatty acid and alcohol metabolism in Pseudomonas putida: functional analysis using random barcode transposon sequencing

MG Thompson, MR Incha, AN Pearson… - Applied and …, 2020 - Am Soc Microbiol
With its ability to catabolize a wide variety of carbon sources and a growing engineering
toolkit, Pseudomonas putida KT2440 is emerging as an important chassis organism for …

Functional analysis of the fatty acid and alcohol metabolism of Pseudomonas putida using RB-TnSeq

MG Thompson, MR Incha, AN Pearson, M Schmidt… - BioRxiv, 2020 - biorxiv.org
With its ability to catabolize a wide variety of carbon sources and a growing engineering
toolkit, Pseudomonas putida KT2440 is emerging as an important chassis organism for …

Nitrogen metabolism in Pseudomonas putida: functional analysis using random barcode transposon sequencing

M Schmidt, AN Pearson, MR Incha… - Applied and …, 2022 - Am Soc Microbiol
Pseudomonas putida KT2440 has long been studied for its diverse and robust metabolisms,
yet many genes and proteins imparting these growth capacities remain uncharacterized …

Modeling and Engineering P. putida for Improved Aromatic Utilization

J Mueller - 2022 - search.proquest.com
Expanded utilization of lignin-derived aromatics could improve alternatives to numerous
chemicals currently produced via non-renewable petrochemicals. To achieve this …

A genome-scale metabolic reconstruction of Pseudomonas putida KT2440: i JN746 as a cell factory

J Nogales, BØ Palsson, I Thiele - BMC systems biology, 2008 - Springer
Background Pseudomonas putida is the best studied pollutant degradative bacteria and is
harnessed by industrial biotechnology to synthesize fine chemicals. Since the publication of …

[PDF][PDF] Massively parallel fitness profiling reveals multiple novel enzymes in Pseudomonas putida lysine metabolism. mBio 10

MG Thompson, JM Blake-Hedges, P Cruz-Morales… - 2019 - researchgate.net
Despite intensive study for 50years, the biochemical and genetic links between lysine
metabolism and central metabolism in Pseudomonas putida remain unresolved. To …

RB-TnSeq identifies genetic targets for improved tolerance of Pseudomonas putida towards compounds relevant to lignin conversion

AJ Borchert, A Bleem, GT Beckham - Metabolic Engineering, 2023 - Elsevier
Lignin-derived mixtures intended for bioconversion commonly contain high concentrations
of aromatic acids, aliphatic acids, and salts. The inherent toxicity of these chemicals places a …

Omics-driven identification and elimination of valerolactam catabolism in Pseudomonas putida KT2440 for increased product titer

MG Thompson, LE Valencia, JM Blake-Hedges… - Metabolic Engineering …, 2019 - Elsevier
Pseudomonas putida is a promising bacterial chassis for metabolic engineering given its
ability to metabolize a wide array of carbon sources, especially aromatic compounds derived …

Massively Parallel Fitness Profiling Reveals Multiple Novel Enzymes in Pseudomonas putida Lysine Metabolism

MG Thompson, JM Blake-Hedges, P Cruz-Morales… - MBio, 2019 - Am Soc Microbiol
Despite intensive study for 50 years, the biochemical and genetic links between lysine
metabolism and central metabolism in Pseudomonas putida remain unresolved. To …