Statins and colchicine co-administration consists of a potentially catastrophic drug–drug
interaction since it provokes myotoxicity, myopathy and various degrees of rhabdomyolysis …

Simvastatin is among the most commonly used prescription medications for cholesterol
reduction and the most common statin-related adverse drug reaction is skeletal muscle …

OBJECTIVE To report a case of acute myopathy after concomitant use of colchicine and
pravastatin. CASE SUMMARY A 65-year-old woman was admitted to the hospital with an …

We report a case of a patient with mild chronic renal insufficiency who had been taking
simvastatin for over a year and developed acute weakness within 3 weeks after the start of …

Myopathy is a life-threatening disease that can be caused, among other things, by the intake
of various medications. Despite the fact that many drug-induced myopathies are well known …

Cholesterol-lowering statins are frequently prescribed for primary and secondary prevention
of ischaemic vascular events. Whereas most patients tolerate statins without problems, statin …

Background Rhabdomyolysis is a widely recognized yet rare complication in statin use.
Rhabdomyolysis might be triggered by the prescription of high doses of statins or by statin …

Colchicine and statins are frequently co‐prescribed for prevention and treatment of
cardiovascular diseases, auto‐inflammatory diseases, and gout. Both are substrates and …

Discussion Two different mechanisms may be responsible for the pathogenesis in our
patient. Drug interactions that potentiate adverse effects may occur when colchicine is …

Statins constitute a cornerstone in the primary and secondary prevention of atherosclerotic
cardiovascular disease (ASCVD). The routine use of these lipid-lowering agents may lead to …