Natural abundance 13C nuclear magnetic resonance spectroscopy identified the
disaccharide trehalose as the major organic osmolyte synthesized by Escherichia coli grown …

Trehalose is a nonreducing disaccharide in which the two glucose units are linked in an α, α-
1, 1-glycosidic linkage. The best known and most widely distributed pathway of trehalose …

Trehalose accumulation is a common cell defense strategy against a variety of stressful
conditions. In particular, our team detected high levels of trehalose in Propionibacterium …

In Escherichia coli, the disaccharide trehalose can be metabolized as a carbon source or be
accumulated as an osmoprotectant under osmotic stress. In hypertonic environments, E. coli …

1.5 kb of otsA gene encoding trehalose synthase has been cloned by PCR amplification.
The DNA fragment was ligated to multi-copy vector and transformed to otsBA deleted and …

Trehalose is a nonreducing disaccharide (α, α-1, 1-diglucose) commonly found in many
fungi and present in particularly high concentrations in quiescent cells and survival forms …

Trehalose is a nonreducing disaccharide composed of two glucose residues bound by an α-
α linkage. First reported in 1832 in rye following ergot infection, trehalose has since been …

An important prelude to bacterial infection is the ability of a pathogen to survive
independently of the host and to withstand environmental stress. The compatible solute …

The analysis of the available Corynebacterium genome sequence data led to the proposal
of the presence of all three known pathways for trehalose biosynthesis in bacteria, ie …

The non-reducing disaccharide trehalose is ubiquitously distributed in nature and commonly
found among prokaryotic and eukaryotic organisms where it is employed as a general stress …