Invertebrate trehalose-6-phosphate synthase gene: genetic architecture, biochemistry, physiological function, and potential applications

B Tang, S Wang, SG Wang, HJ Wang… - Frontiers in …, 2018 - frontiersin.org
The non-reducing disaccharide trehalose is widely distributed among various organisms. It
plays a crucial role as an instant source of energy, being the major blood sugar in insects. In …

Trehalose biosynthesis in response to abiotic stresses

M Iordachescu, R Imai - Journal of integrative plant biology, 2008 - Wiley Online Library
Trehalose is a non‐reducing disaccharide that is present in diverse organisms ranging from
bacteria and fungi to invertebrates, in which it serves as an energy source, osmolyte or …

Trehalose accumulation in rice plants confers high tolerance levels to different abiotic stresses

AK Garg, JK Kim, TG Owens… - Proceedings of the …, 2002 - National Acad Sciences
Trehalose is a nonreducing disaccharide of glucose that functions as a compatible solute in
the stabilization of biological structures under abiotic stress in bacteria, fungi, and …

Trehalose transport and metabolism in Escherichia coli

W Boos, U Ehmann, H Forkl, W Klein… - Journal of …, 1990 - Am Soc Microbiol
Trehalose metabolism in Escherichia coli is complicated by the fact that cells grown at high
osmolarity synthesize internal trehalose as an osmoprotectant, independent of the carbon …

Cloning of a trehalose-6-phosphate synthase gene from Exopalaemon carinicauda and its expression response to bacteria challenge

J Zhang, Y Liu, Y Zhou, W Wang, N Su, Y Sun - Fish & Shellfish …, 2019 - Elsevier
Trehalose, a nonreducing disaccharide, is present in a wide variety of organisms and plays
a key role in many organisms under different stress conditions. In the study, the full-length …

Mycobacterial OtsA structures unveil substrate preference mechanism and allosteric regulation by 2-oxoglutarate and 2-phosphoglycerate

V Mendes, M Acebrón-García-de-Eulate, N Verma… - Mbio, 2019 - Am Soc Microbiol
Trehalose is an essential disaccharide for mycobacteria and a key constituent of several cell
wall glycolipids with fundamental roles in pathogenesis. Mycobacteria possess two …

Involvement of trehalose-6-phosphate synthase in innate immunity of Musca domestica

Y Zhang, F Wang, Q Feng, H Wang, T Tang… - Developmental & …, 2019 - Elsevier
Abstract Trehalose-6-phosphate synthase (TPS) is responsible for synthesizing trehalose,
which is prevalent in crustaceans and insects as blood-sugar. In this paper, a TPS gene from …

Relevance of trehalose in pathogenicity: some general rules, yet many exceptions

H Tournu, A Fiori, P Van Dijck - PLoS Pathogens, 2013 - journals.plos.org
Trehalose, a natural disaccharide, consists of two glucose molecules linked by an a, a-1, 1-
glucoside bond. Apart from its function as a reserve carbohydrate, trehalose is known for its …

Combined effect of betaine and trehalose on osmotic tolerance of Escherichia coli in mineral salts medium

EN Miller, LO Ingram - Biotechnology letters, 2007 - Springer
In mineral salts medium, supplementing with betaine in combination with increased
production of endogenous osmoprotectant from a second copy of the trehalose biosynthetic …

Plant-Type Trehalose Synthetic Pathway in Cryptosporidium and Some Other Apicomplexans

Y Yu, H Zhang, G Zhu - PLoS One, 2010 - journals.plos.org
Background The trehalose synthetic pathway is present in bacteria, fungi, plants and
invertebrate animals, but is absent in vertebrates. This disaccharide mainly functions as a …