Animal models in AIDS research

KJ Sastry, SL Hu, PN Nehete… - Handbook of …, 2021 - api.taylorfrancis.com
Acquired immunodeficiency syndrome (AIDS) is a global epidemic caused by one of two
related retroviruses of the lentivirus family: human immunodeficiency virus (HIV) types 1 and …

HIV/AIDS: in search of an animal model

Z Ambrose, VN KewalRamani, PD Bieniasz… - Trends in …, 2007 - cell.com
AIDS is among the most devastating diseases of our time, claiming the lives of
approximately 3 million people per year. The primary cause of AIDS, human …

[图书][B] In vivo models of HIV disease and control

H Friedman, S Specter, M Bendinelli - 2007 - books.google.com
An AIDS vaccine is still elusive and HIV treatment continues to develop multidrug resistance
at alarming rates. Because of the similarities between HIV and immune deficiency infections …

Nonhuman primate models in AIDS research

DT Evans, G Silvestri - Current Opinion in HIV and AIDS, 2013 - journals.lww.com
In this review, we describe the most recent advances in the use of animal models for
HIV/AIDS research, and will break down these advances in three areas: models for virus …

Developing animal models for AIDS research--progress and problems.

AD Lewis, PR Johnson - Trends in biotechnology, 1995 - europepmc.org
Tremendous advances in our understanding of the human immunodeficiency viruses (HIVs)
have been made through the use of animal models. However, there are limitations inherent …

Experimental animal models of HIV/AIDS for vaccine trials

BO Ibeh, E Ashano - … animal models of human diseases—an …, 2018 - books.google.com
AIDS still persists as a relevant disease in public health and scientific research. There have
been significant advances in HIV research, notably the development of an effective regimen …

Animal models for HIV/AIDS research

T Hatziioannou, DT Evans - Nature Reviews Microbiology, 2012 - nature.com
The AIDS pandemic continues to present us with unique scientific and public health
challenges. Although the development of effective antiretroviral therapy has been a major …

Latest animal models for anti-HIV drug discovery

K Sliva - Expert opinion on drug discovery, 2015 - Taylor & Francis
Introduction: HIV research is limited by the fact that lentiviruses are highly species specific.
The need for appropriate models to promote research has led to the development of many …

Summary of presentations at the NIH/NIAID new humanized rodent models 2007 workshop

H Goldstein - AIDS Research and Therapy, 2008 - Springer
It has long been recognized that a small animal model susceptible to HIV-1 infection with a
functional immune system would be extremely useful in the study of HIV/AIDS pathogenesis …

Evaluation of antiretrovirals in animal models of HIV infection

KKA Van Rompay - Antiviral research, 2010 - Elsevier
Animal models of HIV infection have played an important role in the development of
antiretroviral drugs. Although each animal model has its limitations and never completely …